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| Descriptive Information Fields | |||||||||
| Brief Title † | A Pilot Study of Functional Optical Coherence Tomography for Ocular Imaging | ||||||||
| Official Title † | A Pilot Study of Functional Optical Coherence Tomography for Ocular Imaging | ||||||||
| Brief Summary | At Beckman Laser Institute, University of California, Irvine, we have developed diagnostic device call 'Optical Coherence tomography (OCT)' the imaging technique used in clinical ophthalmology during eye examination, which is imaging the eye (retina) and to diagnose and manages many eye diseases. The study is used to diagnose and manage retinal disease,including choroidal, and optic nerve head vessels in macular degeneration, vitreomacular traction syndrome,diabetic retinopathy, retinoschisis, macular edema, central serous chorioretinopathy, optic nerve disorders, and nerve fiber layer evaluation in glaucoma, and compare these to normal controls. Growing evidence shows that altered blood flow plays a major role in many vision-threatening diseases. Although they account for the majority of cases of severe vision loss and blindness in the United States and worldwide. |
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| Detailed Description | OCT is non-invasive technique, that provides high-resolution cross-sectional images of the retina at unprecedented resolutions as small as a few microns. OCT uses a broadband light source to illuminate the area of study with light in the near infrared spectrum, then obtains static images of tissue structure from interference signals of the back-reflected light. The subject is require to look into an eyepiece on the exam device at a green blinking fixation light illuminated on a dimly lighted background. OCT non-invasive technique use to imaging and will takes from 0.32 seconds to 1.92 seconds to be acquired, then 5-10 seconds to be displayed and determine if the image quality is sufficient. Approximated 4-5 images are taken. |
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| Study Phase | |||||||||
| Study Type † | Observational | ||||||||
| Study Design † | Case Control, Prospective | ||||||||
| Primary Outcome Measure † | |||||||||
| Secondary Outcome Measure † | |||||||||
| Condition † | Glaucoma Diabetic Retinopathy Age-Related Macular Degeneration |
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| Intervention † | Device: OCT | ||||||||
| MEDLINE PMIDs | |||||||||
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| Recruitment Information Fields | |||||||||
| Recruitment Status † | Enrolling by invitation | ||||||||
| Enrollment † | 60 | ||||||||
| Start Date † | January 2007 | ||||||||
| Completion Date | July 2012 | ||||||||
| Eligibility Criteria † | Inclusion Criteria:
Exclusion Criteria:
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| Gender | Both | ||||||||
| Ages | 18 Years and older | ||||||||
| Accepts Healthy Volunteers | Yes | ||||||||
| Contacts †† | |||||||||
| Location Countries † | United States | ||||||||
| Administrative Information Fields | |||||||||
| NCT ID † | NCT00556114 | ||||||||
| Organization ID | RR-01192;PHS- NIH | ||||||||
| Secondary IDs †† | P41-RR01192;NIH-LAMMP | ||||||||
| Study Sponsor † | University of California, Irvine | ||||||||
| Collaborators †† | Beckman Laser Institute Medical Clinic Ophthalmology department, University of California,Irvine |
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| Investigators † |
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| Information Provided By | University of California, Irvine | ||||||||
| Verification Date | December 2007 | ||||||||
| First Received Date † | November 7, 2007 | ||||||||
| Last Updated Date | January 2, 2008 | ||||||||
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