Differential Metabolic Effects of Statins

This study has been completed.
Sponsor:
Information provided by:
Gachon University Gil Medical Center
ClinicalTrials.gov Identifier:
NCT00546559
First received: October 18, 2007
Last updated: August 28, 2008
Last verified: August 2008

October 18, 2007
August 28, 2008
January 2004
Not Provided
Simvastatin and pravastatin may have differential metabolic effects in hypercholesterolemic patients.
Same as current
Complete list of historical versions of study NCT00546559 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Differential Metabolic Effects of Statins
Not Provided

The investigators hypothesized simvastatin and pravastatin may have differential metabolic effects in hypercholesterolemic patients.

Not Provided
Observational
Observational Model: Case Control
Time Perspective: Prospective
Not Provided
Not Provided
Not Provided
Not Provided
Hypercholesterolemia
Drug: statins (simvastatin, pravastatin)
Not Provided
Yada T, Nakata M, Shiraishi T, Kakei M. Inhibition by simvastatin, but not pravastatin, of glucose-induced cytosolic Ca2+ signalling and insulin secretion due to blockade of L-type Ca2+ channels in rat islet beta-cells. Br J Pharmacol. 1999 Mar;126(5):1205-13.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
Not Provided
March 2008
Not Provided

Inclusion Criteria:

  • Low-density lipoprotein cholesterol levels > 130

Exclusion Criteria:

  • Overt liver disease,
  • Chronic renal failure
  • Hypothyroidism
  • Myopathy
  • Uncontrolled diabetes
  • Severe hypertension
Both
25 Years to 75 Years
Not Provided
Contact information is only displayed when the study is recruiting subjects
Korea, Republic of
 
NCT00546559
GMC-200406
Yes
Not Provided
Gachon University Gil Medical Center
Not Provided
Principal Investigator: Kwang K Koh, MD,PhD Gachon University Gil Medical Center
Gachon University Gil Medical Center
August 2008

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP