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Tracheal Mechanics During Bronchoscopy

This study has been completed.
Sponsor:
Information provided by:
Beth Israel Deaconess Medical Center
ClinicalTrials.gov Identifier:
NCT00536315
First received: September 26, 2007
Last updated: February 3, 2010
Last verified: February 2010

September 26, 2007
February 3, 2010
March 1999
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Complete list of historical versions of study NCT00536315 on ClinicalTrials.gov Archive Site
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Tracheal Mechanics During Bronchoscopy
Tracheal Mechanics During Bronchoscopy

The main purpose of this study is use a new type of measurement to help decide what kind of therapy would help people with a collapsing windpipe or tracheomalacia.

This study is to obtain new information about the pressures required to collapse the trachea in patients with and without obstructive pulmonary disease and to describe the relationship between pressures and airflow obstruction. This information will provide normative data not currently available and would establish whether tracheal collapse is due to tracheomalacia. The data may lead to better ways of predicting if a patient would benefit from procedures to prevent tracheal collapse.

Observational
Observational Model: Cohort
Time Perspective: Prospective
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Non-Probability Sample

Healthy control subjects recruited from subjects volunteering for CT or bronchoscopic studies and patients referred for evaluation of possible tracheomalacia.

  • Tracheomalacia
  • Tracheobronchomalacia
Not Provided
  • COPD
    Patients with cough and/or shortness of breath who may have windpipe collapse.
  • Healthy adults
    Subjects without symptoms for comparison.
  • Tracheomalacia
    Patients with cough and/or shortness of breath who may have windpipe collapse.
Loring SH, O'donnell CR, Feller-Kopman DJ, Ernst A. Central airway mechanics and flow limitation in acquired tracheobronchomalacia. Chest. 2007 Apr;131(4):1118-24.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
150
June 2009
Not Provided

Inclusion Criteria:

  • Suspicion of tracheal collapse undergoing bronchoscopy
  • Healthy control subject undergoing bronchoscopy for another purpose.

Exclusion Criteria:

  • Esophageal pathology
  • Tracheostomy
  • inability to follow commands
Both
21 Years and older
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00536315
2001-P-001418
No
Stephen H. Loring, BIDMC
Beth Israel Deaconess Medical Center
Not Provided
Principal Investigator: Stephen H Loring, M.D. Beth Israel Deaconess Medical Center
Beth Israel Deaconess Medical Center
February 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP