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The Effect of Calcium on Fecal Fat and Energy Excretion

The recruitment status of this study is unknown because the information has not been verified recently.
Verified August 2007 by University of Copenhagen.
Recruitment status was  Recruiting
Sponsor:
Collaborators:
Arla Foods
The Danish Dairy Research Foundation, Denmark
FOOD Graduate School, the Royal Veterinary & Agricultural University, Denmark
Danish Research Agency
Information provided by:
University of Copenhagen
ClinicalTrials.gov Identifier:
NCT00519909
First received: August 22, 2007
Last updated: NA
Last verified: August 2007
History: No changes posted

August 22, 2007
August 22, 2007
August 2007
Not Provided
Fecal fat excretion, fecal energy excretion, calcium excretion, cholesterol
Same as current
No Changes Posted
Vitamin D, changes in lipolyse
Same as current
Not Provided
Not Provided
 
The Effect of Calcium on Fecal Fat and Energy Excretion
Not Provided

The overall purpose of this study is to examine the effect of calcium on fecal fat and energy excretion.

Several reports have found inverse associations between calcium intake and body weight. Few intervention studies have shown that a high calcium diet resulted in a greater body weight loss than a low calcium diet. The mechanism is not clear, but one possible explanation is reduced absorption of fat in the gut, due to formation of insoluble calcium fatty acid soaps or binding of bile acids which impairs the formation of micelles.

The aim of this study is to examined if a high calcium intake from dairy products, in diets high or normal in fat content, have an effect on fecal energy and fat excretion, concentrations of substrates involved in energy metabolism and blood pressure.

Interventional
Not Provided
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Open Label
Primary Purpose: Basic Science
Obesity
Other: Dairy calcium
Diets with different content of calcium and fat
  • 1
    Diet with high content of calcium and high content of fat
    Intervention: Other: Dairy calcium
  • 2
    Diet with low content of calcium and high content of fat
    Intervention: Other: Dairy calcium
  • 3
    Diet with high content of calcium and normal content of fat
    Intervention: Other: Dairy calcium
  • 4
    Diet with low content of calcium and normal content of fat
    Intervention: Other: Dairy calcium
  • 5
    Diet with high content of calcium fra supplement and high content of fat
    Intervention: Other: Dairy calcium
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
15
February 2008
Not Provided

Inclusion Criteria:

  • healthy meals
  • BMI 24-31 kg/m2
  • age between 18-50 years

Exclusion Criteria:

  • donation of blood 6 months before and under the study
  • milk allergy, diabetes, hypertension, hyperlipidemia, cronic infectious disease
  • use of dietary supplements 3 months before and under the study
  • smoking
  • elite athletes
  • use of medication
Male
18 Years to 50 Years
Yes
Contact: Arne Astrup, Prof. MD +45 3533 2476 ast@life.ku.dk
Denmark
 
NCT00519909
H-KF-01-144/02
No
Not Provided
University of Copenhagen
  • Arla Foods
  • The Danish Dairy Research Foundation, Denmark
  • FOOD Graduate School, the Royal Veterinary & Agricultural University, Denmark
  • Danish Research Agency
Principal Investigator: Janne K Lorenzen, PhD student Dept. of Human Nutrition, Faculty of Life Sciences, Univerity of Copenhagen
University of Copenhagen
August 2007

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP