Relationship of Peritoneal Solute Transport Rate With VEGF in Children Undergoing Peritoneal Dialysis

The recruitment status of this study is unknown because the information has not been verified recently.
Verified December 2006 by Samsung Medical Center.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Samsung Medical Center
ClinicalTrials.gov Identifier:
NCT00516061
First received: August 13, 2007
Last updated: NA
Last verified: December 2006
History: No changes posted

August 13, 2007
August 13, 2007
December 2006
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No Changes Posted
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Relationship of Peritoneal Solute Transport Rate With VEGF in Children Undergoing Peritoneal Dialysis
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Vascular endothelial growth factor(VEGF) appears to play a central role in the process leading to peritoneal angiogenesis and increased level of VEGF may contribute to high peritoneal small-solute transport rate (PSTR) in continuous ambulatory peritoneal dialysis (CAPD) patients in adult. In children, lymphatic absorption of solute is greater than adult. VEGF-C is related to lymphogenesis, but its role in peritoneal solute transport rate is not known. In this study, we evaluated possible relationship between dialysate VEGF and VEGF-C levels and PSTR in children.

There was significant correlation between dialysate VEGF165 and VEGF-C levels and significant correlation was noted between dialysate VEGF165 and PSTR. Interestingly, dialysate VEGF-C levels had significant correlation with PSTR. High PSTR seems to be related to elevated VEGF-C and VEGF.

Observational
Observational Model: Defined Population
Time Perspective: Cross-Sectional
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Peritoneal Dialysis
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
40
December 2007
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Inclusion Criteria:

  • chronic renal failure
  • children
  • peritoneal dialysis

Exclusion Criteria:

  • acute illness
Both
1 Year to 18 Years
Yes
Contact: Kyung Hoon Paik, M.D. 82-2-3410-1284 drwhite@skku.edu
Korea, Republic of
 
NCT00516061
2006-12-008
Yes
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Samsung Medical Center
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Principal Investigator: Kyung Hoon Paik, M.D. Samsung Medical Center, Sungkyunkwan University School of Medicine
Samsung Medical Center
December 2006

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP