NAC in Preventing CIN in CRF Patients Who Need Enhanced CT Scan in ED

The recruitment status of this study is unknown because the information has not been verified recently.
Verified July 2010 by Seoul National University Hospital.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Seoul National University Hospital
ClinicalTrials.gov Identifier:
NCT00501475
First received: July 13, 2007
Last updated: July 23, 2010
Last verified: July 2010

July 13, 2007
July 23, 2010
March 2007
Not Provided
the rate of CIN [ Time Frame: 3 days after CT scan ]
Same as current
Complete list of historical versions of study NCT00501475 on ClinicalTrials.gov Archive Site
mortality [ Time Frame: 30 days after CT scan ]
Same as current
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Not Provided
 
NAC in Preventing CIN in CRF Patients Who Need Enhanced CT Scan in ED
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The purpose of this study is to evaluate the effect of NAC or sodium bicarbonate in preventing the aggravation of renal function in chronic renal failure when enhanced computed tomography scan is checked in emergency room.

CIN is frequent in CRF patients. However most studies about CIN has been focusing on elective PCI patients. There is no study that the NAC nor sodium bicarbonate would help in preventing CIN in CRF patients who need enhanced CT scan in ED.

Our intention was to investigate the effect of NAC or sodium bicarbonate in preventing the aggravation of renal function in chronic renal failure when enhanced computed tomography scan is checked in emergency room.

Interventional
Phase 4
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator)
Primary Purpose: Prevention
Chronic Renal Failure
Drug: NAC Bicarbonate
Not Provided
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
Not Provided
October 2010
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Inclusion Criteria:

  • CRF patients who need enhanced CT scan

Exclusion Criteria:

  • less than 15 years old
  • hypersensitivity to NAC
  • on dialysis
  • no consent from patient or next of kin
Both
15 Years and older
Not Provided
Contact: Kyuseok Kim, M.D 82-31-787-3049 dremkks@snubh.org
Korea, Republic of
 
NCT00501475
06-2006-084
No
Not Provided
Seoul National University Hospital
Not Provided
Principal Investigator: Kyuseok Kim, MD Seoul National University Bundang Hospital
Seoul National University Hospital
July 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP