Melatonin and Adiponectin in Hypertensive Kidney Transplant

This study has been completed.
Sponsor:
Information provided by:
Sheba Medical Center
ClinicalTrials.gov Identifier:
NCT00498576
First received: July 8, 2007
Last updated: June 29, 2009
Last verified: June 2009

July 8, 2007
June 29, 2009
September 2007
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Complete list of historical versions of study NCT00498576 on ClinicalTrials.gov Archive Site
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Melatonin and Adiponectin in Hypertensive Kidney Transplant
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Recently we have shown that melatonin secretion is impaired in rats with metabolic syndrome. We have also demonstrated that exogenic melatonin supplementation can improve blood pressure profile in nondipper patients.

The aim of this study is to find whether there is a difference between melatonin secretion in hypertensive kidney recipients versus "normal" hypertensive patients. Secondly, to ask if there is any correlation between melatonin secretion and adiponectin levels.

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Observational
Observational Model: Case Control
Time Perspective: Prospective
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Non-Probability Sample

group1- patients from the kidney transplant unit, sheba medical center group2- patients from hypertension unit,sheba medical center

  • Hypertension
  • Kidney Transplant
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  • 1
    kidney transplant with hypertension
  • 2
    hypertensive patients with native kidneys
  • 3
    healthy controls
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
60
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Inclusion Criteria:

  • hypertension
  • kidney transplantation ( group 1)
  • good renal function

Exclusion Criteria:

  • diabetes mellitus
  • cancer
  • renal failure
Both
18 Years to 70 Years
Yes
Contact information is only displayed when the study is recruiting subjects
Israel
 
NCT00498576
SHEBA-07-4730-AL-CTIL
No
leibowitz avshalom, Sheba Medical Center
Sheba Medical Center
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Principal Investigator: Avshalom Leibowitz, MD
Sheba Medical Center
June 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP