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Reducing Health Risk Behavior and Improving Health in Adolescents With Depression
This study is currently recruiting participants.
Study NCT00461539   Information provided by National Institute of Mental Health (NIMH)
First Received: April 16, 2007   Last Updated: March 9, 2009   History of Changes

April 16, 2007
March 9, 2009
October 2007
March 2011   (final data collection date for primary outcome measure)
Composite health risk behavior score [ Time Frame: Measured at Months 6 and 12 ] [ Designated as safety issue: No ]
Composite health risk behavior score (measured 6 and 12 months following study entry)
Complete list of historical versions of study NCT00461539 on ClinicalTrials.gov Archive Site
  • Composite International Diagnostic Interview (CIDI) depression diagnosis [ Time Frame: Measured at Months 6 and 12 ] [ Designated as safety issue: No ]
  • Satisfaction with care, as measured by the SF-12 health survey [ Time Frame: Measured at Months 6 and 12 ] [ Designated as safety issue: No ]
  • Composite International Diagnostic Interview (CIDI) depression diagnosis
  • satisfaction with care, as measured by the SF-12 health survey (all measured 6 and 12 months following study entry)
 
Reducing Health Risk Behavior and Improving Health in Adolescents With Depression
Reducing Health Risk Behavior and Improving Health in Adolescent Depression

This study will determine the effectiveness of a health education intervention in reducing health risk behavior and improving health in adolescents with depression.

Depression is a common disorder among adolescents. If left untreated, it can cause significant disability, illness, and even death. Teens with depression often engage in risky health behaviors, such as smoking, drug and alcohol use, unprotected sex, and unhealthy eating and exercise patterns. By reducing these health risk behaviors, depressed adolescents may be able to avoid negative health consequences and improve their physical and mental health. This study will determine the effectiveness of a health education intervention in reducing risky health behaviors in adolescents with depression.

Participants in this study will be invited to enroll during a visit to a participating primary care clinic. Participants will be randomly assigned to either partake in a health education intervention or receive standard care. Both groups will continue to receive treatment through their primary care clinic. Those participants receiving standard care will be referred to special programs as needed to reduce their involvement in risky health behaviors. Participants assigned to the health education intervention will attend 10 weekly education sessions that will be led by trained health educators. Parents or guardians may be asked to attend sessions depending on their interest in the intervention and the age of the youth participant. Topics covered will include teenage smoking, alcohol and drug abuse, risky sexual behaviors, and obesity. Cognitive-behavioral strategies, role playing, and media clips will be used to stimulate discussion and involvement in the intervention. The intervention will be tailored to target the specific risky behaviors in which each participant engages. Motivational interviewing will also be used to build positive attitudes to support behavior change. All participants will attend follow-up visits to assess behavior change at Months 6 and 12 following study entry.

Phase I, Phase II
Interventional
Treatment, Randomized, Single Blind (Outcomes Assessor), Active Control, Parallel Assignment, Efficacy Study
  • Depression
  • Adolescent Health
  • Other: Treatment as usual
  • Behavioral: Behavioral health intervention
  • Active Comparator: Participants will receive treatment as usual
  • Experimental: Participants will receive the behavioral health intervention
 

*   Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
 
Recruiting
350
April 2011
March 2011   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • CIDI diagnosis of major depression or probable depression based on youth self report
  • Availability of a family member to provide informed consent

Exclusion Criteria:

  • Lacks contact information (e.g., address, telephone number)
  • Any functioning deficits or other characteristics that might interfere with study participation
  • Currently in a living situation that might interfere with study participation (e.g., lives over 1 hour away from the study site)
  • Lacks family available to participate in the intervention
  • Mental retardation
  • Does not speak English or Spanish
Both
13 Years to 18 Years
No
Contact: Joan Asarnow, PhD 310-825-0408 jasarnow@mednet.ucla.edu
Contact: Ancy E. Cherian, PhD 310-794-4962 acherian@mednet.ucla.edu
United States
 
NCT00461539
Joan Asarnow, PhD, University of California, Los Angeles, Semel Institute of Neuroscience and Human Behavior
R01 MH078596, DAHBR 96-BHB
National Institute of Mental Health (NIMH)
 
Principal Investigator: Joan Asarnow, PhD University of California, Los Angeles, Semel Institute of Neuroscience and Human Behavior
National Institute of Mental Health (NIMH)
March 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP