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Aspirin Use and Postoperative Bleeding From Dental Extractions in a Healthy Population

This study has been completed.
Sponsor:
Information provided by:
Carolinas Healthcare System
ClinicalTrials.gov Identifier:
NCT00405613
First received: November 28, 2006
Last updated: NA
Last verified: November 2006
History: No changes posted

November 28, 2006
November 28, 2006
May 2003
Not Provided
Oral bleeding time
Same as current
No Changes Posted
Report of bleeding at phone follow-up at 3-7 (first follow-up) and 40-55 hours (second follow-up)
Same as current
Not Provided
Not Provided
 
Aspirin Use and Postoperative Bleeding From Dental Extractions in a Healthy Population
Aspirin Use and Postoperative Bleeding From Dental Extractions in a Healthy Population

The purpose of this study is to determine if aspirin is associated with bleeding complications following a single tooth extraction

Aspirin is a common chronically administered preventive treatment for cardiovascular disease, but is often discontinued prior to invasive dental procedures because of concern of bleeding complications. As the goal of aspirin is often to prevent MI and stroke, the risk of these CVD outcomes with discontinuation of aspirin must be weighed against the perceived adverse event of bleeding during or following an invasive dental procedure with continuation of aspirin. The current study is a randomized controlled trial evaluating bleeding complications of aspirin vs. placebo in healthy patients schedule for a single tooth extraction.

Interventional
Phase 2
Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double-Blind
Primary Purpose: Treatment
Bleeding Complication
Drug: Aspirin
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
36
December 2005
Not Provided

Inclusion Criteria:

  • Healthy
  • Require a simple tooth extraction

Exclusion Criteria:

  • Use of previous aspirin or NSAID
Both
18 Years to 80 Years
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00405613
HSF-201090
Not Provided
Not Provided
Carolinas Healthcare System
Not Provided
Principal Investigator: Michael T Brennan, DDS,MHS Carolinas Medical Center
Carolinas Healthcare System
November 2006

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP