Anaesthetic Management of Women With Heart Disease For Labor and Delivery

This study has been completed.
Sponsor:
Information provided by:
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
ClinicalTrials.gov Identifier:
NCT00403871
First received: November 23, 2006
Last updated: February 28, 2007
Last verified: February 2007

November 23, 2006
February 28, 2007
November 2002
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Complete list of historical versions of study NCT00403871 on ClinicalTrials.gov Archive Site
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Anaesthetic Management of Women With Heart Disease For Labor and Delivery
Anaesthetic Management of Women With Heart Disease For Labor and Delivery

Heart disease among pregnant women is increasing in incidence. The cardiovascular changes associated with pregnancy may be particularly hazardous for both mother and fetus in a subset of these patients. The period of greatest risk is peripartum while these patients are under the care of the obstetrician and anesthesiologist. We will evaluate the anesthetic management of all women with heart disease whose pregnancies were followed at the University Health Network and/or Mount Sinai Hospital between 1986 and 2001.

Heart disease among pregnant women is increasing in incidence. The cardiovascular changes associated with pregnancy may be particularly hazardous for both mother and fetus in a subset of these patients. The period of greatest risk is peripartum while these patients are under the care of the obstetrician and anesthesiologist. Exposing a compromised patient to general anesthesia is further complicated by the cardiovascular stress response to intubation and surgery, the cardiorespiratory implications of mechanical ventilation, the cardiac depression and vasodilation from general anesthetics, residual post-operative respiratory depression from general anesthetics and narcotics and the stress of weaning from mechanical ventilation and post-operative pain.

In the Adult Congenital Heart Program, obstetric patients are followed the by a specialized team of cardiologists, obstetricians and anesthesiologists who also follow all pregnant women referred with acquired cardiac disease. From this referral practice approximately 100 patients per year are now followed during their pregnancy and delivery. In conjunction with the ongoing system we intend to identify all parturients who delivered at the University Health Network (Toronto General Hospital) or Mount Sinai Hospital between the years 1986 and 2001. We will evaluate the anesthetic management of all women with heart disease whose pregnancies were followed at the University Health Network and/or Mount Sinai Hospital between 1986 and 2001.

Observational
Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Longitudinal
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  • Heart Diseases
  • Pregnancy
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
700
June 2005
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Inclusion Criteria:

  • Pregnant women with congenital or acquired heart disease
  • Pregnant women with arrhythmias are also included providing they had had symptomatic tachyarrhythmias or bradyarrhythmias requiring treatment

Exclusion Criteria:

  • Women with isolated mitral valve prolapse including those with mild to moderated mitral regurgitation
  • Women referred for termination of pregnancy
Female
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No
Contact information is only displayed when the study is recruiting subjects
Canada
 
NCT00403871
06-05, 02-0211-E
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Samuel Lunenfeld Research Institute, Mount Sinai Hospital
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Principal Investigator: Eric Goldszmidt, MD Mount Sinai Hosiptal
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
February 2007

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP