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Cognitive Remediation in Early Substance Abuse Treatment

This study has been terminated.
(The intervention could not be successfully carried out in the SADP setting because of issues independent of the cognitive training intervention.)
Sponsor:
Information provided by:
Department of Veterans Affairs
ClinicalTrials.gov Identifier:
NCT00334217
First received: June 2, 2006
Last updated: June 17, 2009
Last verified: June 2009

June 2, 2006
June 17, 2009
August 2005
August 2007   (final data collection date for primary outcome measure)
Cognitive improvement and adherence to substance abuse treatment [ Time Frame: 6 month follow-up ] [ Designated as safety issue: No ]
Post-treatment neuropsychological testing, 6-month follow-up testing
Complete list of historical versions of study NCT00334217 on ClinicalTrials.gov Archive Site
Not Provided
Alcohol use disorder inventory, Alcohol/Substance Use Inventory, Beck Depression Inventory
Not Provided
Not Provided
 
Cognitive Remediation in Early Substance Abuse Treatment
Cognitive Remediation in the Initial Phase of Substance Abuse Treatment: Feasibility and Efficacy

This study is for the purpose of determining whether cognitive remediation may improve cognition and treatment response in patients entering substance abuse day treatment

Background: Patients entering substance abuse treatment display cognitive deficits that may reduce their ability to benefit from their treatment. While there is considerable variety in the severity and types of cognitive impairment found in newly recovering patients, problems with attention, memory and executive function are very common. Since treatment requires sustained attention, remembering what is learned, integrating that knowledge and applying it to recovery, impairment in underlying cognitive processes makes successful treatment less likely. Although cognitive functioning improves with sustained sobriety, it is during the early phase of recovery that most patients receive the most intensive treatment. Recent research has suggested that cognitive remediation exercises during this early phase may speed up the return of cognitive functioning and in so doing may have a direct effect on whether patients find the treatment useful and complete their treatment. By keeping patients in treatment longer, cognitive remediation may have an indirect effect on substance abuse outcomes.

Objectives: To pilot test the introduction of cognitive remediation at the Substance Abuse Day Treatment Program (SADP) at the Errara Community Care Center. Aims are 1) to assess the receptivity of patients to the intervention by determining rates of agreement to participate, 2) to determine the number of cognitive remediation sessions that patients are willing to engage in, 3) to assess a variety of cognitive remediation tasks for their acceptability, 4) to evaluate neuropsychological improvements using pre-post assessment, 5) to evaluate its effects on substance abuse treatment participation, and 6) to evaluate its effects on substance abuse outcomes at 6 months follow-up.

Design: Randomized clinical trial of cognitive remediation with an active control condition with observations at baseline, end of treatment and 6-months from intake

Interventional
Not Provided
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Substance-Related Disorders
Behavioral: Cognitive Remediation
PSS Cogrehab
  • Experimental: 1
    PSS CogRehab exercises
    Intervention: Behavioral: Cognitive Remediation
  • No Intervention: 2
    On-line computer games

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Terminated
40
December 2008
August 2007   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Veterans participating in a substance abuse day treatment program at the Errara Community Center

Exclusion Criteria:

Both
Not Provided
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00334217
O3108R
Not Provided
Bell, Morris - Principal Investigator, Department of Veterans Affairs
Department of Veterans Affairs
Not Provided
Principal Investigator: Morris D Bell, PhD VA Connecticut Health Care System (West Haven)
Department of Veterans Affairs
June 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP