The Effects of a 16-Week Individualized, Intensive Strength Training Program in Patients With Rheumatoid Arthritis

This study has been completed.
Sponsor:
Collaborator:
Centocor, Inc.
Information provided by:
University of Arizona
ClinicalTrials.gov Identifier:
NCT00327275
First received: May 16, 2006
Last updated: NA
Last verified: May 2006
History: No changes posted

May 16, 2006
May 16, 2006
March 2004
Not Provided
  • Strength
  • Body Composition
  • Function
  • Pain
Same as current
No Changes Posted
  • Quality of Life
  • Disease Activity
  • Fatigue
Same as current
Not Provided
Not Provided
 
The Effects of a 16-Week Individualized, Intensive Strength Training Program in Patients With Rheumatoid Arthritis
The Strength Training and Remicade Study

To assess the effects of a 16-week individualized, intensive strength training program in patients with rheumatoid arthritis. Primary and secondary outcomes include: strength and body composition, function, disease activity, pain, quality of life.

We hypothesized that improvements would be seen in all of the above outcomes.

Not Provided
Interventional
Not Provided
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Rheumatoid Arthritis
Behavioral: strength training
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
35
January 2005
Not Provided

Inclusion Criteria:

  • Males and females with RA
  • Over 18 years of age
  • ACR Functional Class I and II
  • Taking Remicade >4 months

Exclusion Criteria:

  • Presence of comorbid conditions contraindicated to exercise, including, but not limited to:

    1. heart disease
    2. severe osteoporosis: (if >50 years): T score < -3.0 for hip or spine excluded; T score <-2.5 for hip or spine w/o current treatment)
    3. (all potential subjects) previous non-traumatic fractures
    4. uncontrolled BP
  • BMI >40
  • Regular use of assistive walking device which would interfere with ability to lift weights
  • Currently or within the last 3 months participating in aerobic exercise > 150 minutes a week
  • Currently or within the last 3 months participating in any regular strength training activities
  • Presence of neurological impairment that directly limits ability to perform exercise
  • Participation in concurrent exercise study
  • Any reason for which the investigator deems it would not be in the patient’s best interest to continue in the study
  • Plans to move away from site within next 1 year
Both
18 Years and older
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00327275
080192
Not Provided
Not Provided
University of Arizona
Centocor, Inc.
Principal Investigator: Hilary G Flint-Wagner, PhD, MPH Idaho State University
University of Arizona
May 2006

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP