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Incidence of Delirium in Hip Fracture Patients Randomized to Regular Hypnotics vs Placebo

This study has been terminated.
(Slow inclusion resulting in premature termination due to logistics)
Sponsor:
Collaborator:
IMK Fonden
Information provided by:
Hvidovre University Hospital
ClinicalTrials.gov Identifier:
NCT00286936
First received: February 3, 2006
Last updated: August 29, 2011
Last verified: September 2006

February 3, 2006
August 29, 2011
February 2004
Not Provided
Incidence and severity of postoperative delirium
Same as current
Complete list of historical versions of study NCT00286936 on ClinicalTrials.gov Archive Site
  • Sleep quality
  • mobilization
  • loss of functional ability
  • length of stay
  • sedation
  • nocturnal nursing events
Same as current
Not Provided
Not Provided
 
Incidence of Delirium in Hip Fracture Patients Randomized to Regular Hypnotics vs Placebo
Incidence of Delirium in Hip Fracture Patients Randomized to Regular Hypnotics vs Placebo

To examine the influence of regular hypnotic therapy on the incidence of delirium after hip fracture surgery

Delirium is prevalent after hip fracture surgery. Delirium has been linked to postoperative sleep disturbances. Zolpidem is a non-benzodiazepine hypnotic that preserves REM sleep. The present study investigates the incidence of delirium in hip fracture patients randomized to Zolpidem treatment 5 mg vs placebo in the perioperative phase.

Interventional
Phase 4
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double-Blind
Primary Purpose: Prevention
  • Hip Fracture
  • Delirium
Drug: Zolpidem
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Terminated
96
January 2007
Not Provided

Inclusion Criteria:

  • Primary hip fracture, no substance abuse, no regular opioid, corticosteroid or benzodiazepine therapy, hepatic insufficiency, myastenia gravis, allergies to drug components

Exclusion Criteria:

  • Severe respiratory insufficiency
Both
70 Years and older
No
Contact information is only displayed when the study is recruiting subjects
Denmark
 
NCT00286936
HHSG-RCT-05
Not Provided
Not Provided
Hvidovre University Hospital
IMK Fonden
Study Director: Nicolai B Foss, MD Hvidovre University Hospital
Hvidovre University Hospital
September 2006

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP