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Prevention of Suicide in Primary Care Elderly: Collaborative Trial (PROSPECT)

This study has been completed.
Sponsor:
Collaborators:
University of Pennsylvania
University of Pittsburgh
Forest Laboratories
The John A. Hartford Foundation
Information provided by:
Weill Medical College of Cornell University
ClinicalTrials.gov Identifier:
NCT00279682
First received: January 17, 2006
Last updated: NA
Last verified: January 2006
History: No changes posted

January 17, 2006
January 17, 2006
May 1999
Not Provided
  • Hamilton Depression Rating Scale
  • Scale for Suicide Ideation
Same as current
No Changes Posted
  • All cause and cause-specific mortality
  • disability (Sf12; instrumental activities of daily living)
Same as current
Not Provided
Not Provided
 
Prevention of Suicide in Primary Care Elderly: Collaborative Trial (PROSPECT)
Prevention of Suicide in Primary Care Elderly: Collaborative Trial

The purpose of this study was to determine the effect of a primary care intervention on reducing suicidal ideation and depression in older patients.

Suicide rates are highest in late life; the majority of older adults who die by suicide have seen a primary care physician in preceding months. Depression is the strongest risk factor for late-life suicide and for suicide’s precursor, suicidal ideation.

The aim of the study was to determine the extent to which an intervention taht combined treatment guidelines with care management reduced rates of depression and suicide ideation in older primary care patients. The study randomized 20 primary care practices from New York City, Philadelphia, and Pittsburgh regions into intervention or usual car. The used a two-stage sampling design that resulted in a representative sample with an oversample of depressed patients (total n=1238 subjects including 598 with a depression diagnosis and 640 with no depression diagnosis). Patients were assessed at baseline, 4, 8, 12, 18 and 24 months.

Interventional
Phase 4
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Prevention
  • Depression
  • Suicide, Attempted
Behavioral: treatment guidelines and depression care management
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
1200
August 2003
Not Provided

Inclusion Criteria:

upcoming appointment with primary care clinician

Exclusion Criteria:

  • inability to give consent
  • minimental status examination <18
  • ability to communicate in English
Both
60 Years and older
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00279682
R01MH59366, R01MH59380, R01MH59381
Not Provided
Not Provided
Weill Medical College of Cornell University
  • University of Pennsylvania
  • University of Pittsburgh
  • National Institute of Mental Health (NIMH)
  • Forest Laboratories
  • The John A. Hartford Foundation
Principal Investigator: George S Alexopoulos, MD Weill Medical College of Cornell University
Principal Investigator: Ira Katz, MD. Ph.D. University of Pennsylvania
Principal Investigator: Charles F Reynolds, MD University of Pittsburgh
Weill Medical College of Cornell University
January 2006

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP