The Role of Nebulized Budesonide in the Treatment of Acute Exacerbations of COPD

This study has been terminated.
Sponsor:
Information provided by:
Inonu University
ClinicalTrials.gov Identifier:
NCT00274222
First received: January 9, 2006
Last updated: NA
Last verified: January 2006
History: No changes posted

January 9, 2006
January 9, 2006
January 2003
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No Changes Posted
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The Role of Nebulized Budesonide in the Treatment of Acute Exacerbations of COPD
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This study was designed to evaluate the hypothesis that nebulized budesonide) might be an alternative to systemic corticosteroids (SC) in the treatment of patients with acute exacerbations of COPD (AECOPD).

Patients, hospitalized with AECOPD, were randomized into three groups. Group I received only bronchodilator treatment (BDT), Group II received SC (40 mg prednisolon) plus BDT, and Group III received nebulized budesonide (NB)(1500 mcg qid) plus BDT. Improvement rates in multiple parameters during 10-day hospitalization, and acute exacerbation and re-hospitalization rates within one-month after discharge were compared between the groups.

Observational
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COPD Acute Exacerbation
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Terminated
120
October 2005
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Inclusion Criteria:

  • COPD patients who were admitted to our pulmonary department for an acute exacerbation were prospectively enrolled in the study

Exclusion Criteria:

  • COPD patients hospitalized with specific reasons like pneumonia, pulmonary emboli, congestive heart failure, pneumothorax etc. as the cause of acute exacerbation, or patients with risk of imminent respiratory failure requiring mechanical ventilation or direct admission to the ICU were excluded.
Both
18 Years to 80 Years
No
Contact information is only displayed when the study is recruiting subjects
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NCT00274222
2006-3
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Inonu University
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Study Chair: HAKAN GUNEN, MD INONU UNIVERSITY PULMONARY MEDICINE
Inonu University
January 2006

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP