Continuous Delivery of Levodopa in Patients With Advanced Idiopathic Parkinsons Disease - Cost-benefit

This study has been completed.
Sponsor:
Collaborator:
Solvay Pharmaceuticals
Information provided by (Responsible Party):
Christofer Lundqvist, Akershus University College
ClinicalTrials.gov Identifier:
NCT00272688
First received: January 6, 2006
Last updated: October 31, 2011
Last verified: October 2011

January 6, 2006
October 31, 2011
January 2006
May 2009   (final data collection date for primary outcome measure)
  • Marginal cost per QALY of replacing conventional treatment with intraduodenal levodopa [ Time Frame: one year ] [ Designated as safety issue: No ]
  • Quality of life at three, six, nine and twelve months(Assessed by Nottingham Health Profile (NHP), Parkinson Disease Questionnaire (PDQ39), 15D Quality of life) [ Designated as safety issue: No ]
Not Provided
Complete list of historical versions of study NCT00272688 on ClinicalTrials.gov Archive Site
Parkinson related function at three, six, nine and twelve months(UPDRS, Hoehn and Yahr scores, Schwab and England) [ Designated as safety issue: No ]
Not Provided
Not Provided
Not Provided
 
Continuous Delivery of Levodopa in Patients With Advanced Idiopathic Parkinsons Disease - Cost-benefit
Continuous Delivery of Levodopa/Carbidopa (Duodopa) in Patients With Advanced Idiopathic Parkinsons Disease - a Health Economic Evaluation

An open, observational health economic study to estimate marginal cost and health consequences of replacing conventional Parkinsons disease therapy with intraduodenal levodopa administered continuously

Not Provided
Interventional
Phase 4
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Parkinson Disease
Drug: Levodopa (drug), intraduodenal administration
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
10
May 2009
May 2009   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Clinical diagnosis of of idiopathic Parkinsons disease
  • Motor fluctuations despite optimised per oral treatment

Exclusion Criteria:

  • Severe dementia, confusion, psychosis or depression
  • Patients with contraindications against levodopa treatment
Both
Not Provided
No
Contact information is only displayed when the study is recruiting subjects
Norway
 
NCT00272688
Duo-HRQoL-2
Not Provided
Christofer Lundqvist, Akershus University College
University Hospital, Akershus
Solvay Pharmaceuticals
Principal Investigator: Christofer Lundqvist, PhD, M.D. HØKH - Helse Ost Health Services Research Centre, Akershus University Hospital, Norway
Principal Investigator: Antonie Beiske, PhD, M.D. Dept Neurology, Akershus University Hospital, Norway
University Hospital, Akershus
October 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP