Multifunctional Substrate for Early Detection of Oxidative Stress Susceptibility and Application to Parkinson's Disease
This study is currently recruiting participants.
Verified December 2005 by Hillel Yaffe Medical Center
Sponsor:
Hillel Yaffe Medical Center
Collaborator:
Technion, Israel Institute of Technology
Information provided by:
Hillel Yaffe Medical Center
ClinicalTrials.gov Identifier:
NCT00271141
First received: December 29, 2005
Last updated: NA
Last verified: December 2005
History: No changes posted
| Tracking Information | |||||
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| First Received Date ICMJE | December 29, 2005 | ||||
| Last Updated Date | December 29, 2005 | ||||
| Start Date ICMJE | May 2005 | ||||
| Primary Completion Date | Not Provided | ||||
| Current Primary Outcome Measures ICMJE | Not Provided | ||||
| Original Primary Outcome Measures ICMJE | Not Provided | ||||
| Change History | No Changes Posted | ||||
| Current Secondary Outcome Measures ICMJE | Not Provided | ||||
| Original Secondary Outcome Measures ICMJE | Not Provided | ||||
| Current Other Outcome Measures ICMJE | Not Provided | ||||
| Original Other Outcome Measures ICMJE | Not Provided | ||||
| Descriptive Information | |||||
| Brief Title ICMJE | Multifunctional Substrate for Early Detection of Oxidative Stress Susceptibility and Application to Parkinson's Disease | ||||
| Official Title ICMJE | Multifunctional Substrate for Early Detection of Oxidative Stress Susceptibility and Application to Parkinson's Disease | ||||
| Brief Summary | The proposed work is based on the detection of a novel molecule for sensitivity to oxidative stress in humans in venous blood |
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| Detailed Description | Since alterations in mitochondrial functions in platelets and lymphocytes have been detected in Parkinson's disease we plan to monitor the metabolism a a new molecule (LTG) in the blood samples of Parkinson's disease patients and compare them to controls. We shall use 10 cc of venous blood and analyze serum, white blood cells and platelets. We shall not extract nor use DNA.The main purpose is to develop a marker for Parkinson's disease in venous blood. |
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| Study Type ICMJE | Observational | ||||
| Study Design ICMJE | Additional Descriptors: Convenience Sample Primary Purpose: Screening Time Perspective: Cross-Sectional Time Perspective: Retrospective |
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| Target Follow-Up Duration | Not Provided | ||||
| Biospecimen | Not Provided | ||||
| Sampling Method | Not Provided | ||||
| Study Population | Not Provided | ||||
| Condition ICMJE |
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| Intervention ICMJE | Not Provided | ||||
| Study Group/Cohort (s) | Not Provided | ||||
| Publications * | Not Provided | ||||
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* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline. |
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| Recruitment Information | |||||
| Recruitment Status ICMJE | Recruiting | ||||
| Enrollment ICMJE | 500 | ||||
| Completion Date | December 2015 | ||||
| Primary Completion Date | Not Provided | ||||
| Eligibility Criteria ICMJE | Inclusion Criteria: Parkinson's disease Healthy control - Exclusion Criteria: None - |
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| Gender | Both | ||||
| Ages | 18 Years and older | ||||
| Accepts Healthy Volunteers | Yes | ||||
| Contacts ICMJE |
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| Location Countries ICMJE | Israel | ||||
| Administrative Information | |||||
| NCT Number ICMJE | NCT00271141 | ||||
| Other Study ID Numbers ICMJE | hy11/2005 | ||||
| Has Data Monitoring Committee | Not Provided | ||||
| Responsible Party | Not Provided | ||||
| Study Sponsor ICMJE | Hillel Yaffe Medical Center | ||||
| Collaborators ICMJE | Technion, Israel Institute of Technology | ||||
| Investigators ICMJE |
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| Information Provided By | Hillel Yaffe Medical Center | ||||
| Verification Date | December 2005 | ||||
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ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP |
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