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Radiofrequency Ablation of Ectopic Atrial Tachycardia

This study has been terminated.
(significant conclusive data has been collected)
Sponsor:
Information provided by:
Children's Healthcare of Atlanta
ClinicalTrials.gov Identifier:
NCT00267982
First received: December 20, 2005
Last updated: July 5, 2011
Last verified: June 2011

December 20, 2005
July 5, 2011
August 1992
August 2003   (final data collection date for primary outcome measure)
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Complete list of historical versions of study NCT00267982 on ClinicalTrials.gov Archive Site
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Radiofrequency Ablation of Ectopic Atrial Tachycardia
A Retrospective Review of Outcomes Related to Radiofrequency Ablation of Ectopic Atrial Tachycardia

A retrospective chart review will be performed on 50 patients who received RFA for the treatment of EAT between August 1992 and August 2003 at Children's Healthcare of Atlanta.

The use of the CARTO/Biosense catheter has improved outcomes with decreased radiation exposure to patients.

Ectopic Atrial Tachycardia (EAT) is a relatively rare arrhythmia in the pediatric population. It is defined by a run of more than 3 premature atrial contractions together. In EAT, the arrhythmia tends to increase in rate over a period of time and then slows down gradually to a normal rhythm. Ectopic Atrial Tachycardia (EAT) is mostly encountered in patients with structurally normal hearts however, occasionally physicians do observe this type of disorder in children following surgery for congenital heart defects. Current reports suggest that EAT occurs in approximately 1 in 10,000 children (Hamilton, 2002).

Children with EAT usually present with a multitude of symptoms. The most common symptoms associated with pediatric EAT are palpitations, chest pain, lightheadedness, presyncope, and dyspnea. Other symptoms can include exercise intolerance and congestive heart failure. These are usually late manifestations. In the patients with tachycardia induced CM, the time of development of CM is dependent on the rate and duration of the tachycardia however, in most cases, dilation is present upon diagnosis. This CM can be reversed with successful treatment of the arrhythmia.

The treatment for chronic EAT includes medications such as adenosine and for difficult to control cases, Radiofrequency Ablation (RFA). RF ablation has been successful in curing EAT, with success rates ranging from 75-100%. It has been shown that the complication rates are similar to other RF ablation procedures, with a higher risk of recurrence (Hamilton, 2002).

At Children's Healthcare of Atlanta, the cardiac catheterization lab performs approximately 10 Radiofrequency ablations for EAT each year. The goal of this retrospective review is to assess the frequency of recurrence of the EAT among a subset of patients receiving treatment between August 1992 - August 2003

Observational
Observational Model: Cohort
Time Perspective: Retrospective
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Non-Probability Sample

The study population is subjects received RFA for treatment of EAT between August 2992 and August 2003 at Children's Healthcare of Atlanta

Congenital Disorders
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Terminated
25
February 2008
August 2003   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • 50 patients who received RFA for treatment of EAT between August 2992 and August 2003
  • Treatment at Children's Healthcare of Atlanta

Exclusion Criteria:

  • those who do not meet inclusion criteria
Both
up to 21 Years
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00267982
03-064
No
Patrick Frias, MD, Children's Healthcare of Atlanta
Children's Healthcare of Atlanta
Not Provided
Principal Investigator: Patrick A Frias, MD Sibley Heart Center Cardiology of Children's Healthcare of Atlanta
Children's Healthcare of Atlanta
June 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP