The National Danish Schizophrenia Project

The recruitment status of this study is unknown because the information has not been verified recently.
Verified July 1997 by University of Copenhagen.
Recruitment status was  Active, not recruiting
Sponsor:
Collaborator:
University of Aarhus
Information provided by:
University of Copenhagen
ClinicalTrials.gov Identifier:
NCT00221585
First received: September 16, 2005
Last updated: November 6, 2006
Last verified: July 1997

September 16, 2005
November 6, 2006
October 1997
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Complete list of historical versions of study NCT00221585 on ClinicalTrials.gov Archive Site
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The National Danish Schizophrenia Project
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A prospective, longitudinal, multi-centre investigation (16 centres), including 562 patients, consecutively referred during two years, with a first-episode psychosis of ICD-10, F-2 type. Patients were treated with: 1) ‘Supportive psychodynamic psychotherapy as a supplement to treatment as usual’, 2) an ‘Integrated, assertive, psychosocial and educational treatment programme’, and 3) ‘Treatment as usual’.

The study is a prospective, comparative, longitudinal study with an intervention period of a minimum of two years and a registration of data at baseline and 1, 2 and 5 years after inclusion. Three sub-cohorts with different treatment modalities were designed:

Treatment1: 119 patients were, in addition to TaU, offered SPP, i.e. a scheduled manualised supportive individual psychotherapy (1 session of 45 min. per week, for a period of 1-3 years) and/or group psychotherapy (1 session of 60 min. per week for a period of 1-3 years). Anti-psychotic medication was given in doses based on individual needs; Treatment 2: 139 patients were offered IT, i.e. a scheduled, two-year long programme consisting of assertive community treatment, psycho-educational multi-family treatment (a.m. McFarlane, consisting of 4-6 families including the patients, meeting 1½ hour every second week for 1½ year), social skills training (concerning medication, self-management, coping with symptoms, conversational skills, problem and conflict solving skills), and antipsychotic medication (low dose strategy). This project, OPUS, has been described in detail elsewhere

Observational
Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Longitudinal
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Schizophrenia
Behavioral: Psychosocial treatment/Psychodynamic treatment
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Rosenbaum B, Valbak K, Harder S, Knudsen P, Koster A, Lajer M, Lindhardt A, Winther G, Petersen L, Jorgensen P, Nordentoft M, Andreasen AH. The Danish National Schizophrenia Project: prospective, comparative longitudinal treatment study of first-episode psychosis. Br J Psychiatry. 2005 May;186:394-9.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Active, not recruiting
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July 2005
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Inclusion Criteria:

consecutively referred patients, age 16-35 years, who suffered from a first-episode psychosis of the schizophrenic spectrum disorder (ICD-10, DF 20-29).

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Exclusion Criteria:

  • patients suffering from mental retardation or other organic brain damage, and patients who were not proficient enough in Danish due to their foreign origins.
Both
16 Years to 35 Years
No
Contact information is only displayed when the study is recruiting subjects
Denmark
 
NCT00221585
5490-184
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University of Copenhagen
University of Aarhus
Study Director: Bent Rosenbaum, DMSci Psychiatric Center Glostrup, Dernmark
University of Copenhagen
July 1997

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP