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Family Cognitive Behavioral Therapy for Preventing Depression in Children

This study is currently recruiting participants.
Information provided by National Institute of Mental Health (NIMH)

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Descriptive Information Fields
Brief Title  Family Cognitive Behavioral Therapy for Preventing Depression in Children
Official Title  Family Cognitive Behavioral Prevention of Depression in Children of Parents With a History of Major Depressive Disorder
Brief Summary

This study will determine the effectiveness of cognitive behavioral therapy (CBT) versus educational treatment in preventing depression in the children of parents with a history of depression.

Detailed Description

Depression is a serious condition that can affect a person's work, relationships, and quality of life. Studies have shown that children of depressed parents are at a higher risk for developing depression than those whose parents have not experienced depression. Safe and effective treatments that can help prevent children of depressed parents from becoming depressed are needed. This study will compare CBT to depression education to determine which is more effective in preventing depression in the children of depressed parents.

Families will be randomly assigned to receive weekly sessions of either CBT or depression education for 12 weeks. Parents in the CBT group will be taught skills to more effectively raise their children and to better manage their depressive symptoms; their children will be taught skills to cope with the stress of their parents' depression. Families in the education group will be informed about the ways that depression can affect individuals with depression and their families.

Study visits will occur at study entry and at Week 12. Several follow-up visits will occur for up to 2 years after the interventional part of the study. At each visit, a clinician will make direct observations of the depressed parent's interaction with his or her children. In addition, families will be interviewed and will complete questionnaires about the parent's depressive symptoms and family interaction.

Study Phase Phase III
Study Type  Interventional
Study Design  Prevention, Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study
Primary Outcome Measure  Depression, anxiety, and disruptive behavior problems in children; measured at baseline and Week 12
Depression in parents; measured at baseline and Week 12
Secondary Outcome Measure  Parenting skills of parents; measured at baseline and Week 12
Coping skills of children; measured at baseline and Week 12
Quality of parent-child relationship; measured at baseline and Week 12
Condition  Depression
Intervention  Behavioral: Family Cognitive Behavioral Therapy (CBT)
Behavioral: Depression Education
MEDLINE PMIDs
Links
Recruitment Information Fields
Recruitment Status  Recruiting
Enrollment  750
Start Date  July 2004
Completion Date
Eligibility Criteria 

Inclusion Criteria for Participating Families:

  • Families with at least one parent with a history of depression during the life of his or her child
  • Families with at least one child between the age of 10 and 15
  • Parent or guardian willing to provide informed consent for participating children

Exclusion Criteria for All Participants:

  • Parent with bipolar disorder or schizophrenia
  • Child with conduct disorder or pervasive developmental disorder
Gender Both
Ages 10 Years and older
Accepts Healthy Volunteers No
Contacts ††
Contact: Bruce E. Compas, PhD     615-322-8306     bruce.compas@vanderbilt.edu    
Location Countries  United States
Administrative Information Fields
NCT ID  NCT00183482
Organization ID R01 MH69940
Secondary IDs †† DDTR B4-ARD
Study Sponsor  National Institute of Mental Health (NIMH)
Collaborators ††
Investigators 
Principal Investigator:     Bruce E. Compas, PhD     Vanderbilt University    
Information Provided By National Institute of Mental Health (NIMH)
Verification Date June 2006
First Received Date  September 13, 2005
Last Updated Date October 23, 2007

 †    Required WHO trial registration data element.
††   WHO trial registration data element that is required only if it exists.




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