Family Cognitive Behavioral Therapy for Preventing Depression in Children

The recruitment status of this study is unknown because the information has not been verified recently.
Verified June 2006 by National Institute of Mental Health (NIMH).
Recruitment status was  Recruiting
Sponsor:
Information provided by:
National Institute of Mental Health (NIMH)
ClinicalTrials.gov Identifier:
NCT00183482
First received: September 13, 2005
Last updated: October 23, 2007
Last verified: June 2006

September 13, 2005
October 23, 2007
July 2004
Not Provided
  • Depression, anxiety, and disruptive behavior problems in children; measured at baseline and Week 12
  • Depression in parents; measured at baseline and Week 12
  • Depression, anxiety, and disruptive behavior problems in children; measured at Week 12 and up to 2 years after study end date
  • Depression in parents; measured at Week 12 and up to 2 years after study end date
Complete list of historical versions of study NCT00183482 on ClinicalTrials.gov Archive Site
  • Parenting skills of parents; measured at baseline and Week 12
  • Coping skills of children; measured at baseline and Week 12
  • Quality of parent-child relationship; measured at baseline and Week 12
  • Parenting skills of parents; measured at Week 12 and up to 2 years after study end date
  • Coping skills of children; measured at Week 12 and up to 2 years after study end date
  • Quality of parent-child relationship; measured at Week 12 and up to 2 years after study end date
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Family Cognitive Behavioral Therapy for Preventing Depression in Children
Family Cognitive Behavioral Prevention of Depression in Children of Parents With a History of Major Depressive Disorder

This study will determine the effectiveness of cognitive behavioral therapy (CBT) versus educational treatment in preventing depression in the children of parents with a history of depression.

Depression is a serious condition that can affect a person's work, relationships, and quality of life. Studies have shown that children of depressed parents are at a higher risk for developing depression than those whose parents have not experienced depression. Safe and effective treatments that can help prevent children of depressed parents from becoming depressed are needed. This study will compare CBT to depression education to determine which is more effective in preventing depression in the children of depressed parents.

Families will be randomly assigned to receive weekly sessions of either CBT or depression education for 12 weeks. Parents in the CBT group will be taught skills to more effectively raise their children and to better manage their depressive symptoms; their children will be taught skills to cope with the stress of their parents' depression. Families in the education group will be informed about the ways that depression can affect individuals with depression and their families.

Study visits will occur at study entry and at Week 12. Several follow-up visits will occur for up to 2 years after the interventional part of the study. At each visit, a clinician will make direct observations of the depressed parent's interaction with his or her children. In addition, families will be interviewed and will complete questionnaires about the parent's depressive symptoms and family interaction.

Interventional
Phase 3
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Prevention
Depression
  • Behavioral: Family Cognitive Behavioral Therapy (CBT)
  • Behavioral: Depression Education
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
750
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Inclusion Criteria for Participating Families:

  • Families with at least one parent with a history of depression during the life of his or her child
  • Families with at least one child between the age of 10 and 15
  • Parent or guardian willing to provide informed consent for participating children

Exclusion Criteria for All Participants:

  • Parent with bipolar disorder or schizophrenia
  • Child with conduct disorder or pervasive developmental disorder
Both
10 Years and older
No
Contact: Bruce E. Compas, PhD 615-322-8306 bruce.compas@vanderbilt.edu
United States
 
NCT00183482
R01 MH69940, DDTR B4-ARD
Not Provided
Not Provided
National Institute of Mental Health (NIMH)
Not Provided
Principal Investigator: Bruce E. Compas, PhD Vanderbilt University
National Institute of Mental Health (NIMH)
June 2006

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP