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Study of Breath-holding as a Means to Reduce Tumor Motion From Breathing

This study has been terminated.
(Drs Okunieff and ODell have left the University of Rochester)
Sponsor:
Information provided by (Responsible Party):
University of Rochester
ClinicalTrials.gov Identifier:
NCT00178477
First received: September 13, 2005
Last updated: April 18, 2013
Last verified: April 2013

September 13, 2005
April 18, 2013
January 2002
January 2011   (final data collection date for primary outcome measure)
Tumor Motion Related to Breathing as Determined From MRI Images [ Time Frame: 20 - 30 seconds ] [ Designated as safety issue: No ]
  1. Determine the typical and maximal tumor 3D displacements over the respiratory cycle and how these values vary depending on the tumor location
  2. Determine the reproducibility of target position over multiple breath-holds
  3. Determine the variability across patients in respiratory-derived lesion motion and target position reproducibility over multiple breath-holds
Not Provided
Complete list of historical versions of study NCT00178477 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Study of Breath-holding as a Means to Reduce Tumor Motion From Breathing
Feasibility Study for Gated External-Beam Radiotherapy for Patients With Internal, Extra-cranial Tumors

The purpose of this research study is to evaluate typical tumor motion caused by breathing using MRI and can help determine whether simple passive breathing and/or breath-holding could be used for the future treatment of similar lung and liver tumors using radiation therapy radiosurgery techniques.

Not Provided
Interventional
Not Provided
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Neoplasm, Metastatic
Procedure: MRI with breath-holding
Breath holding for diminished tumor motion.
Experimental: Breath-holding
MRI with breath-holding
Intervention: Procedure: MRI with breath-holding
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Terminated
10
January 2011
January 2011   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • The patient is enrolled on U8700 RSRB # A Phase II Study For Using Radiosurgery On Limited Metastases Of Breast Cancer or U9700 A Pilot Study For Using Radiosurgery On Limited Metastases.
  • ≥ 18 years of age
  • has given Informed consent

Exclusion Criteria:

-Contraindications for any MRI procedure

Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00178477
URCC 3701
No
University of Rochester
University of Rochester
Not Provided
Principal Investigator: Walter O'Dell, PhD University of Rochester
University of Rochester
April 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP