Vaccination in the Peripheral Stem Cell Transplant Setting for Multiple Myeloma

This study has been completed.
Sponsor:
Information provided by:
Cell Genesys
ClinicalTrials.gov Identifier:
NCT00116441
First received: June 29, 2005
Last updated: December 18, 2007
Last verified: December 2007

June 29, 2005
December 18, 2007
October 2000
Not Provided
Multiple myeloma
Same as current
Complete list of historical versions of study NCT00116441 on ClinicalTrials.gov Archive Site
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Vaccination in the Peripheral Stem Cell Transplant Setting for Multiple Myeloma
Vaccination in the Peripheral Stem Cell Transplant Setting for Multiple Myeloma: The Use of Autologous Tumor Cells With an Allogeneic GM-CSF Producing Cell Line

The purpose of this study is to evaluate the safety and efficacy of vaccination with autologous myeloma cells and an allogeneic granulocyte-macrophage colony stimulating factor (GM-CSF) producing cell line.

Not Provided
Interventional
Phase 1
Phase 2
Allocation: Non-Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Multiple Myeloma
Biological: Therapeutic Cellular Vaccine, GM-CSF Producing
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
22
October 2004
Not Provided

Inclusion Criteria:

  • De novo multiple myeloma
  • ECOG 0-2
  • No serious co-morbid illnesses and adequate organ function
  • > 4 weeks from systemic steroids

Exclusion Criteria:

  • No existing secondary malignancies and no history of secondary malignancies in the past 5 years
  • No active autoimmune disease
Both
18 Years to 70 Years
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00116441
K-0007, K-0007
Not Provided
Not Provided
Cell Genesys
Not Provided
Not Provided
Cell Genesys
December 2007

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP