Now Available for Public Comment: Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials

The Effects of Overfeeding on Obesity-Prone (OP) and Obesity-Resistant (OR) Women

This study has been completed.
Sponsor:
Information provided by:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
ClinicalTrials.gov Identifier:
NCT00072917
First received: November 12, 2003
Last updated: January 15, 2010
Last verified: January 2010

November 12, 2003
January 15, 2010
October 2003
Not Provided
Not Provided
Not Provided
Complete list of historical versions of study NCT00072917 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
The Effects of Overfeeding on Obesity-Prone (OP) and Obesity-Resistant (OR) Women
The Effects of Overfeeding on Obesity-Prone (OP) and Obesity-Resistant (OR) Women

This is a longitudinal cohort study of how the responses to a 3 day period of controlled overfeeding relate to subsequent weight gain. We hypothesize that thin individuals are resistant to weight gain because they respond to periods of overfeeding by increasing fat oxidation, reducing food intake, and increasing physical activity relative to those who gain weight over time.

Not Provided
Observational
Observational Model: Cohort
Time Perspective: Prospective
Not Provided
Retention:   Samples With DNA
Description:

Blood and urine

Non-Probability Sample

Subjects have been recruited through advertisements in local news media and on the internet

  • Obesity
  • Thinness
  • Weight Gain
Not Provided
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
100
June 2008
Not Provided
  • Half of the subjects will be women, half will be men,
  • age 25-35,
  • a range of BMI's from 19-27, for the 'thin subjects' there should be no 1st degree relatives with a BMI>30.
  • Subjects should not engage in planned physical activity more than 3 hrs per week.
  • For the obesity prone group there should be at least 1 1st degree relative with a BMI>30.
Both
25 Years to 35 Years
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00072917
OVOPOB DK62874 (complted), DK62874
Yes
Daniel H. Bessesen, MD, University of Colorado School of Medicine
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Not Provided
Not Provided
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
January 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP