Protection Against Benzene Toxicity

This study has been completed.
Sponsor:
Information provided by:
National Institute of Environmental Health Sciences (NIEHS)
ClinicalTrials.gov Identifier:
NCT00011453
First received: February 21, 2001
Last updated: June 23, 2005
Last verified: July 2002

February 21, 2001
June 23, 2005
July 1998
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Complete list of historical versions of study NCT00011453 on ClinicalTrials.gov Archive Site
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Protection Against Benzene Toxicity
NQO1 in Protection Against Benzene Toxicity

We are investigating the role of an enzyme (NQO1) in protection against the bone marrow toxicity of the occupational and environmental toxicant benzene. All of the proposed studies involve use of human bone marrow cells in-vitro to define mechanisms of NQO1-mediated protection. Cells are obtained from healthy volunteers and protocols have undergone IRB review and approval.

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Observational
Primary Purpose: Screening
Time Perspective: Prospective
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  • Leukemia
  • Aplastic Anemia
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
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June 2001
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Healthy adult volunteers with blood counts in normal ranges and without evidence of hepatitis or HIV infection.

Both
21 Years to 65 Years
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00011453
9554-CP-001
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National Institute of Environmental Health Sciences (NIEHS)
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National Institute of Environmental Health Sciences (NIEHS)
July 2002

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP