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Chagas Disease as an Undiagnosed Type of Cardiomyopathy in the United States

This study has been completed.
Sponsor:
Information provided by:
National Heart, Lung, and Blood Institute (NHLBI)
ClinicalTrials.gov Identifier:
NCT00005455
First received: May 25, 2000
Last updated: June 23, 2005
Last verified: November 2001

May 25, 2000
June 23, 2005
January 1993
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Complete list of historical versions of study NCT00005455 on ClinicalTrials.gov Archive Site
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Chagas Disease as an Undiagnosed Type of Cardiomyopathy in the United States
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A detailed review was made of data pertinent to the occurrence of chronic Chagas disease in the United States.

BACKGROUND:

In Latin America, 16 to 18 million individuals are thought to have Chagas' disease and 90 million are considered to be at risk of infection. In the United States, the occurrence of Chagas' disease is virtually limited to individuals who have resided in Latin America where they acquired the infection, and then migrated to this country.

DESIGN NARRATIVE:

Data on the prevalence of positive serologic reactions for Trypanosoma cruzi (a protozoan causing Chagas cardiomyopathy) serve for calculating that a total of up to 74,000 Latin Americans residing in the United States have the chronic form of chagasic cardiomyopathy. The vast majority of these individuals are either undiagnosed, or misdiagnosed as having idiopathic dilated cardiomyopathy or coronary artery disease. Vector transmission of T. cruzi infection is very unlikely to occur in the United States because of variations in biological behavior of local species of insect vectors and because of changes in human living conditions. Transfusion of blood from infected but asymptomatic individuals is considered the most important mechanism of transmission of this disorder in the United States.

Observational
Observational Model: Natural History
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  • Heart Diseases
  • Myocardial Diseases
  • Chagas Disease
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
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December 1993
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No eligibility criteria

Male
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No
Contact information is only displayed when the study is recruiting subjects
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NCT00005455
4488
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National Heart, Lung, and Blood Institute (NHLBI)
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National Heart, Lung, and Blood Institute (NHLBI)
November 2001

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP