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Cocaine Effects in Humans: Physiology and Behavior - 1

This study has been completed.
Sponsor:
Collaborator:
Columbia University
Information provided by:
National Institute on Drug Abuse (NIDA)
ClinicalTrials.gov Identifier:
NCT00000200
First received: September 20, 1999
Last updated: September 10, 2008
Last verified: September 2008

September 20, 1999
September 10, 2008
January 1997
January 1998   (final data collection date for primary outcome measure)
  • Interaction of cocaine and meds on cardio [ Time Frame: 3 hr ] [ Designated as safety issue: Yes ]
  • Interaction of cocaine & meds on coc's subjective [ Time Frame: 3 hr ] [ Designated as safety issue: Yes ]
  • Effects of medication on cocaine craving [ Time Frame: 3 hr ] [ Designated as safety issue: No ]
  • Interaction of cocaine and meds on cardio
  • Interaction of cocaine & meds on coc's subjective
  • Effects of medication on cocaine craving
Complete list of historical versions of study NCT00000200 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Cocaine Effects in Humans: Physiology and Behavior - 1
Cocaine Effects in Humans: Physiology and Behavior

The purpose of this study is to compare the effects of buprenorphine or methadone maintenance on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving, in opiate-dependent cocaine users.

Not Provided
Interventional
Phase 2
Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Double Blind (Subject, Caregiver)
Primary Purpose: Treatment
Cocaine-Related Disorders
Drug: Methadone
normal maintenance dose
Not Provided
Foltin RW, Fischman MW. Effects of methadone or buprenorphine maintenance on the subjective and reinforcing effects of intravenous cocaine in humans. J Pharmacol Exp Ther. 1996 Sep;278(3):1153-64.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
19
January 1998
January 1998   (final data collection date for primary outcome measure)

Please contact site for information.

Both
18 Years to 45 Years
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00000200
NIDA-03818-1, R01-03818-1
Yes
Not Provided
National Institute on Drug Abuse (NIDA)
Columbia University
Principal Investigator: Marian Fischman, Ph.D. Columbia University
National Institute on Drug Abuse (NIDA)
September 2008

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP