Amplitude and Rate of Intrinsic Feedback During Treadmill Training for Parkinson's Disease
Treadmill training has been shown to be beneficial for reducing motor symptoms of Parkinson's disease (PD). The mechanisms for the therapeutic effects of treadmill training remain unknown. However, specific types of intrinsic feedback generated from muscle spindles (detect changes in length of muscle) and golgi tendon organs (detect muscle force) seem to be an important factor for achieving the reductions in motor scores. This study will compare a treadmill program that generates a high rate of intrinsic feedback to a treadmill program focused on generating a high magnitude of intrinsic feedback.
Behavioral: rate group
Behavioral: magnitude treadmill group
Behavioral: regular treadmill walking
|Study Design:||Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Outcomes Assessor)
Primary Purpose: Treatment
- Motor section of the Unified Parkinson's Disease Rating Scale (UPDRS-III) [ Time Frame: Pre assessments are conducted in the week prior to the treadmill program. Post are conducted during the week immediately following the program. Changes after the 6 week treadmill program are being examined ] [ Designated as safety issue: No ]A measure of the motor symptom severity within Parkinsons. UPDRS III is a qualitative assessment performed by a trained clinician. Specifically, a change in UPDRS III from pre to post is the main outcome measure.
- Spatiotemporal aspects of gait [ Time Frame: pre test occurs within the week prior to the start of the treadmill training program. Post testing will occur during the week immediately following the 6 week treadmill training program. ] [ Designated as safety issue: No ]
Participants will walk on a pressure sensitive GAITRite carpet (Sparta, NJ), at both comfortable and fast paced walking speeds. Changes in gait characteristics from pre to post are what is being examined.
Quantitative measures of gait such as step time, step length, walking velocity, and others will be used in the analysis.
Spotters are always present to ensure safety during this assessment.
- Static Posturography (balance/postural control) [ Time Frame: pre test occurs within the week prior to the start of the treadmill training program. Post testing will occur during the week immediately following the 6 week treadmill training program. ] [ Designated as safety issue: No ]A Balance SD system from BIODEX (Shirley, NY) will be used to assess postural control. Changes from pre to post are what is being examined.
|Study Start Date:||October 2013|
|Estimated Study Completion Date:||March 2014|
|Estimated Primary Completion Date:||March 2014 (Final data collection date for primary outcome measure)|
Experimental: Treadmill Intervention 1: Rate Group
Participants in this condition will walk with a cadence (steps per minute) that is approximately 35% faster than comfortable walking pace. In this condition, participants will maintain a step length that is similar to that of their comfortable walking pace.
Behavioral: rate group
walking with a high cadence (steps per minute)
Experimental: Magnitude treadmill group
In this condition participants will walk on a treadmill with weights on their ankles to elicit a greater magnitude of instrinsic feedback from force sensitive golgi tendon organs
|Behavioral: magnitude treadmill group|
Placebo Comparator: regular treadmill walking
participants will walk at a comfortable self-selected pace on a treadmill
|Behavioral: regular treadmill walking|
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