Fetuin A in Hashimoto Thyroiditis
Fetuin-A levels are reported to be low as a negative acute phase reactant in systemical inflammatory situations. Hashimoto thyroiditis is characterized with inflammation. In this study, we hypothesised that the serum fetuin A levels could be found to be low due to inflammation in patients with Hashimoto thyroiditis
|Study Type:||Observational [Patient Registry]|
|Study Design:||Time Perspective: Cross-Sectional|
|Target Follow-Up Duration:||1 Day|
|Official Title:||Fetuin A as a New Marker of Inflammation in Hashimoto Thyroiditis|
- Comparison of serum fetuin A levels between patients with Hashimoto thyroiditis and healthy subjects [ Time Frame: 1 day (The blood samples were obtained on the same day participants arrived to outpatient clinics.) ] [ Designated as safety issue: No ]
|Study Start Date:||May 2012|
|Study Completion Date:||October 2012|
|Primary Completion Date:||October 2012 (Final data collection date for primary outcome measure)|
|Group of Hashimoto thyroiditis patients|
|Healty control group|
Patients ≥ 20 years of age being followed up at the outpatient clinics of the Internal Medicine Department in Medeniyet University Goztepe Training and Research Hospital and fulfilling the eligibility criteria will be included in the study. Approval of the local ethics committee and informed consent of the participants will be received for the study. The study is conducted in accordance with the Declaration of Helsinki. Demographic characteristics, concomitant diseases, smoking and alcohol drinking habits, concomitant medication usage, anthropometric and biochemistry data of the eligible patients will be recorded. Patient group will consist of patients with newly diagnosed Hashimoto thyroiditis and the control group will consist of healthy volunteers.
Groups will be compared according to their demographic, an¬thropometric and biochemistry data and serum fetuin-A levels. In order to detect the relationship between the serum fetuin-A levels and clinical features, correlation analyses will be done.