Spectral Dynamics and Speech Understanding by Hearing Impaired People

This study is enrolling participants by invitation only.
Sponsor:
Information provided by (Responsible Party):
Department of Veterans Affairs
ClinicalTrials.gov Identifier:
NCT01867515
First received: May 20, 2013
Last updated: September 3, 2014
Last verified: September 2014
  Purpose

The purpose of this program of research is to understand the perception of the dynamic spectral properties of speech by hearing-impaired listeners, with the long-term goal of improving speech understanding by these individuals in adverse listening conditions. The proposed research compares the performance of normally-hearing and hearing-impaired listeners on measures of speech understanding in the presence of different types of signal distortion and speech understanding of signals with enhanced spectral dynamics. A computational model based on the amount of potential information available in speech will be used to quantify differences in speech intelligibility due to hearing status and stimulus characteristics.


Condition
Hearing Loss, Sensorineural

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Spectral Dynamics and Speech Understanding by Hearing Impaired People

Resource links provided by NLM:


Further study details as provided by Department of Veterans Affairs:

Primary Outcome Measures:
  • Perception of spectral change in speech [ Time Frame: Three years ] [ Designated as safety issue: No ]
    The experimental approach compares speech identification performance among normal hearing listeners, hearing-impaired listeners, and normal hearing listeners with simulated hearing impairment. Tasks will be carried out in quiet and in the presence of 2 levels of continuous, speech-shaped background noise. Experimental metrics will be percentage of correct/incorrect speech identification and patterns of response confusions. Error rates and error patterns will be compared among the three listener groups. Performance will also be interpreted relative to the output of a computational model.


Secondary Outcome Measures:
  • Speech understanding of signals with targeted spectral change enhancement [ Time Frame: Three years ] [ Designated as safety issue: No ]
    The experimental approach compares speech identification performance among normal hearing listeners, hearing-impaired listeners, and normal hearing listeners with simulated hearing impairment for stimuli that have been enhanced in the frequency region of the second formant. Tasks will be carried out in quiet and in the presence of two levels of continuous, speech-shaped background noise. Experimental metrics will be percentage of correct/incorrect speech identification and patterns of response confusions.


Biospecimen Retention:   None Retained

None collected


Estimated Enrollment: 120
Study Start Date: August 2013
Estimated Study Completion Date: September 2016
Estimated Primary Completion Date: September 2016 (Final data collection date for primary outcome measure)
Groups/Cohorts
Hearing-Impaired
Individuals with mild-to-moderate levels of hearing loss
Normal Hearing
Individuals with normal hearing
Simulated Hearing-Impaired
Individuals with normal hearing for whom hearing loss will be simulated through the use of a spectrally-shaped broadband noise

Detailed Description:

This is a behavioral study of human auditory perception. Each experiment in this study involves prospective data collection from three types of listeners. The experimental listeners will be people with sensorineural hearing loss and the control listeners will either be subjects with normal hearing or normal-hearing listeners for whom hearing loss will be simulated through the use of a spectrally-shaped broadband noise. The tasks of the subjects in this study involve either listening to synthesized sounds over earphones while seated comfortably in a sound-treated booth, and making responses indicating the subject's auditory perception of these sounds by touching specific areas on a touch-screen terminal; or, listening to recorded, acoustically modified syllables, words, or sentences over earphones and making responses indicating the subject's identification.

  Eligibility

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

community sample

Criteria

Inclusion Criteria:

  • individuals with hearing thresholds of 20 dB HL or better at all octave frequencies between 250 Hz and 4000 Hz
  • or, individuals with bilateral sensorineural hearing losses with thresholds between 25 and 70 dB HL and no losses greater than 70 dB HL at frequencies of 4000 Hz or below

Exclusion Criteria:

  • a conductive hearing impairment or other otological pathology
  • hearing thresholds greater than 70 dB HL at any frequencies of 4000 Hz or below or pure-tone averages (averaged across 500, 1000, and 2000 Hz) of greater than 65 dB HL
  • bilateral differences greater than 20 dB at any frequency below 4000 Hz
  • an inability to complete the experimental tasks
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01867515

Locations
United States, Oregon
VA Medical Center, Portland
Portland, Oregon, United States, 97201
Sponsors and Collaborators
Investigators
Principal Investigator: Michelle R Molis, PhD VA Medical Center, Portland
  More Information

No publications provided

Responsible Party: Department of Veterans Affairs
ClinicalTrials.gov Identifier: NCT01867515     History of Changes
Other Study ID Numbers: C1020-R, 1I01RX001020-01
Study First Received: May 20, 2013
Last Updated: September 3, 2014
Health Authority: United States: Federal Government

Keywords provided by Department of Veterans Affairs:
Hearing
Hearing Loss, sensorineural
Speech Perception

Additional relevant MeSH terms:
Deafness
Hearing Loss
Hearing Loss, Sensorineural
Ear Diseases
Hearing Disorders
Nervous System Diseases
Neurologic Manifestations
Otorhinolaryngologic Diseases
Sensation Disorders
Signs and Symptoms

ClinicalTrials.gov processed this record on October 29, 2014