Text Size

Impact of Visceral Fat on the Pathogenesis of Age-related Macular Degeneration

This study is ongoing, but not recruiting participants.
Sponsor:
Information provided by (Responsible Party):
Rudolf Foundation Clinic
ClinicalTrials.gov Identifier:
NCT01777984
First received: December 1, 2011
Last updated: January 24, 2013
Last verified: January 2013
History of Changes
  Purpose

The purpose of this study is to determine the relationship among the body fat distribution, especially the visceral fat, in patients with age-related macular degeneration in comparison to patients with a normal fundus.


Condition
Age-related Macular Degeneration

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Impact of Visceral Fat on the Pathogenesis of Age-related Macular Degeneration

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Rudolf Foundation Clinic:

Primary Outcome Measures:
  • visceral fat ratio [ Time Frame: 1 day ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Leptin, Amyloid, TNF alpha, CRP [ Time Frame: 1 day ] [ Designated as safety issue: No ]

Estimated Enrollment: 100
Study Start Date: December 2009
Estimated Study Completion Date: December 2013
Estimated Primary Completion Date: May 2013 (Final data collection date for primary outcome measure)
Detailed Description:

In this study the investigators want to examine the relationship among visceral fat, serum leptin levels, and high-sensitive CRP (hsCRP), Tnf-alpha, Amyloid alpha and Amyloid Beta serum levels in patients with age-related macular degeneration in comparison to patients with a normal fundus.

  Eligibility

Ages Eligible for Study:   60 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

patients with age-related macular degeneration, over 60

Criteria

Inclusion Criteria:

  • man and women over 18 years old
  • filled informed consent
  • diagnosis of age-related macular degeneration

Exclusion Criteria:

  • inherited retinal disease
  • other acquired retinal macular disease
  • missing informed consent
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01777984

Locations
Austria
Rudolf Foundation Clinic
Vienna, Austria, 1030
Sponsors and Collaborators
Rudolf Foundation Clinic
Investigators
Principal Investigator: Susanne Binder Rudolf Foundation Clinic
  More Information

No publications provided

Responsible Party: Rudolf Foundation Clinic
ClinicalTrials.gov Identifier: NCT01777984     History of Changes
Other Study ID Numbers: EK-08-122-0708
Study First Received: December 1, 2011
Last Updated: January 24, 2013
Health Authority: Austria: Ethikkommission

Additional relevant MeSH terms:
Macular Degeneration
Retinal Degeneration
Retinal Diseases
Eye Diseases

ClinicalTrials.gov processed this record on May 16, 2013