Impact of Visceral Fat on the Pathogenesis of Age-related Macular Degeneration

This study is ongoing, but not recruiting participants.
Sponsor:
Information provided by (Responsible Party):
Rudolf Foundation Clinic
ClinicalTrials.gov Identifier:
NCT01777984
First received: December 1, 2011
Last updated: January 24, 2013
Last verified: January 2013
  Purpose

The purpose of this study is to determine the relationship among the body fat distribution, especially the visceral fat, in patients with age-related macular degeneration in comparison to patients with a normal fundus.


Condition
Age-related Macular Degeneration

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Impact of Visceral Fat on the Pathogenesis of Age-related Macular Degeneration

Resource links provided by NLM:


Further study details as provided by Rudolf Foundation Clinic:

Primary Outcome Measures:
  • visceral fat ratio [ Time Frame: 1 day ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Leptin, Amyloid, TNF alpha, CRP [ Time Frame: 1 day ] [ Designated as safety issue: No ]

Estimated Enrollment: 100
Study Start Date: December 2009
Estimated Study Completion Date: December 2013
Estimated Primary Completion Date: May 2013 (Final data collection date for primary outcome measure)
Detailed Description:

In this study the investigators want to examine the relationship among visceral fat, serum leptin levels, and high-sensitive CRP (hsCRP), Tnf-alpha, Amyloid alpha and Amyloid Beta serum levels in patients with age-related macular degeneration in comparison to patients with a normal fundus.

  Eligibility

Ages Eligible for Study:   60 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

patients with age-related macular degeneration, over 60

Criteria

Inclusion Criteria:

  • man and women over 18 years old
  • filled informed consent
  • diagnosis of age-related macular degeneration

Exclusion Criteria:

  • inherited retinal disease
  • other acquired retinal macular disease
  • missing informed consent
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01777984

Locations
Austria
Rudolf Foundation Clinic
Vienna, Austria, 1030
Sponsors and Collaborators
Rudolf Foundation Clinic
Investigators
Principal Investigator: Susanne Binder Rudolf Foundation Clinic
  More Information

No publications provided

Responsible Party: Rudolf Foundation Clinic
ClinicalTrials.gov Identifier: NCT01777984     History of Changes
Other Study ID Numbers: EK-08-122-0708
Study First Received: December 1, 2011
Last Updated: January 24, 2013
Health Authority: Austria: Ethikkommission

Additional relevant MeSH terms:
Macular Degeneration
Retinal Degeneration
Retinal Diseases
Eye Diseases

ClinicalTrials.gov processed this record on July 26, 2014