The Role of Mid-Life Adiposity in Functional Brain Connectivity
This study is ongoing, but not recruiting participants.
Information provided by (Responsible Party):
Piero Antuono, MD, Medical College of Wisconsin
First received: January 24, 2013
Last updated: September 15, 2014
Last verified: September 2014
The purpose of the study is to use functional MRI (fMRI) to measure brain connectivity in middle-aged individuals with different levels of body fat. The ultimate goal of this research is to develop an early diagnostic tool for Alzheimer's disease.
||Observational Model: Case Control
Time Perspective: Cross-Sectional
||The Role of Mid-Life Adiposity in Functional Brain Connectivity
Biospecimen Retention: Samples With DNA
Primary Outcome Measures:
- Brain connectivity measured by fMRI [ Time Frame: One visit ] [ Designated as safety issue: No ]
| Estimated Enrollment:
| Study Start Date:
| Estimated Study Completion Date:
| Estimated Primary Completion Date:
||June 2015 (Final data collection date for primary outcome measure)
Participants will have one visit for:
- Blood draw
- Body composition scan
- Cognitive screen
- Neurological exam
- MRI scan
The visit will take approximately 3 hours.
|Ages Eligible for Study:
||45 Years to 65 Years
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Healthy volunteers from the community
- 45-65 years of age
- Normal memory
- General good physical health
- History of stroke or neurological disease
- Seizures or head injury with loss of consciousness within the last five years
- Ferrous (magnetic) or electronic implants (due to the magnet in the MRI scanner)
More detailed inclusion/exclusion criteria must be met in order to qualify for the study. The study coordinator will determine eligibility.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01777789
|Medical College of Wisconsin/Froedtert Hospital
|Milwaukee, Wisconsin, United States, 53226 |
Medical College of Wisconsin
||Piero Antuono, MD
||Medical College of Wisconsin
No publications provided
||Piero Antuono, MD, Professor, Medical College of Wisconsin
History of Changes
|Other Study ID Numbers:
|Study First Received:
||January 24, 2013
||September 15, 2014
||United States: Institutional Review Board
Keywords provided by Medical College of Wisconsin:
ClinicalTrials.gov processed this record on October 23, 2014