Systematic Genetic Analysis of Phenomenology and Treatment Response in Mood Disorders
The purpose of this study is to identify genetic changes that can interact with environmental factors to influence people's susceptibility to disease and responses to medical treatments. Therefore, we would like to study the genetic materials from you as part of the study. We will compare the DNA sequence from people with certain clinical features (observable characteristics, determined by both genes and environment) and/or treatment responses to the DNA from people without those clinical features and/or medication treatment responses to find the DNA sequence differences that exist. By combining this information with information from your medical records, it may be possible to identify the genetic changes that influence people's responses to different medical treatments. This project could lead to more knowledge about why certain people respond differently to a treatment. With such knowledge, future treatments potentially could become customized to a patient's unique genetic make-up.
You will be one of participants enrolled in this research.
Major Depressive Disorder
|Study Type:||Observational [Patient Registry]|
|Study Design:||Observational Model: Ecologic or Community
Time Perspective: Cross-Sectional
|Target Follow-Up Duration:||10 Years|
- Identify genetic variations contributing to inter-patient variability in disease susceptibility [ Time Frame: Day 1 ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples With DNA
|Study Start Date:||January 2013|
|Estimated Primary Completion Date:||January 2015 (Final data collection date for primary outcome measure)|