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Optimizing Triage and Hospitalisation In Adult General Medical Emergency Patients: the TRIAGE Study

This study is currently recruiting participants. (see Contacts and Locations)
Verified April 2013 by University Hospital, Basel, Switzerland
Sponsor:
Information provided by (Responsible Party):
Philipp Schuetz, University Hospital, Basel, Switzerland
ClinicalTrials.gov Identifier:
NCT01768494
First received: January 9, 2013
Last updated: April 2, 2013
Last verified: April 2013
  Purpose

Patients presenting to the emergency department (ED) currently face inacceptable delays in initial treatment, and long and costly hospital stays due to suboptimal initial triage. Accurate ED triage should focus not only on initial treatment priority, but also on prediction of medical risk and nursing needs to improve site of care decision and to simplify early discharge management. Herein, we propose a large prospective cohort study to optimize initial patient triage for (a) better determination of initial treatment priority, (b) overall risk and need for inhospital treatment and (c) early assessment of post-acute nursing needs.


Condition
Emergencies

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Optimizing Triage and Hospitalisation In Adult General Medical Emergency Patients: the TRIAGE Study

Resource links provided by NLM:


Further study details as provided by University Hospital, Basel, Switzerland:

Primary Outcome Measures:
  • Initial triage priority [ Time Frame: within 30 days ] [ Designated as safety issue: No ]
    Initial triage priority adjudicated by the attending ED physician. Attending ED physicians will classify all patients at ED discharge as either high triage priority or low triage priority in respect to the time patients need to be seen by a physician based on all available information at ED discharge

  • Adverse 30 day outcome (death or intensive care unit admission) within 30 days following ED admission [ Time Frame: Within 30 days of ED admission ] [ Designated as safety issue: No ]
    Adverse 30 day outcome (death or intensive care unit admission) within the hospital stay and within 30 days following ED admission

  • Care needs after hospital discharge [ Time Frame: Within 30 days ] [ Designated as safety issue: No ]
    Care needs after hospital discharge will be defined as transfer of patients to a post-acute care institution (i.e. transition to a nursing home and others).


Secondary Outcome Measures:
  • Time to first physician contact [ Time Frame: Within 30 days ] [ Designated as safety issue: No ]
    Time to first physician contact as assessed in the nursing chart; we will investigate this endpoint stratified by patient risk, i.e. we will compare time to first physician contact in high-triage-priority and low-triage-priority patients and stratified by different diagnoses.

  • Time to initiation of adequate medical therapy [ Time Frame: Wihtin 30 days ] [ Designated as safety issue: No ]
    Time to initiation of adequate medical therapy in predefined subgroups (e.g., antibiotic therapy for infections, door to needle time for myocardial infarction; early goal directed therapy in sepsis patients, pain relief medication in patients presenting with pain, blood pressure control in patients with a hypertensive crisis); we will further assess time to discharge from the ED to the ward.

  • Satisfaction with care [ Time Frame: Within 30 days ] [ Designated as safety issue: No ]
    Satisfaction with care as assessed with a systematic questionnaire in the day 30 telephone interview

  • Hospital costs [ Time Frame: Within 30 days ] [ Designated as safety issue: No ]
    Overall hospital costs as assessed by the electronic medical records


Biospecimen Retention:   Samples Without DNA

Left over blood samples of routinely collect blood tubes on admission will be asserved and aliquoted for later batch analysis of blood biomarkers (bio-bank)


Estimated Enrollment: 5000
Study Start Date: March 2013
Estimated Study Completion Date: September 2014
Estimated Primary Completion Date: May 2014 (Final data collection date for primary outcome measure)
Detailed Description:

Background: Patients presenting to the emergency department (ED) currently face inacceptable delays in initial treatment, and long and costly hospital stays due to suboptimal initial triage. Accurate ED triage should focus not only on initial treatment priority, but also on prediction of medical risk and nursing needs to improve site of care decision and to simplify early discharge management. Different triage scores have been proposed, such as the Manchester Triage Score (MTS). Yet, these scores focus only on treatment priority, have suboptimal performance and lack validation in the Swiss Health care system. Because the MTS will be introduced into clinical routine of the Kantonsspital Aarau, we propose a large prospective cohort study to optimize initial patient triage. Specifically, the aim of this trial is to derive a three part triage algorithm to better predict (a) treatment priority; (b) medical risk and thus need for inhospital treatment; (c) post-acute care needs of patient's at the most proximal time point of ED admission.

Methods / Design: Prospective, observational, cohort study. We will include all consecutive medical patients seeking ED care into this observational registry. There will be no exclusions except for non-adult and non-medical patients. Vital signs will be recorded and left over blood samples will be stored for later batch analysis of blood markers. Upon ED discharge, the post-acute care score will be recorded. Attending ED physicians will adjudicate triage priority based on all available results at the time of discharge. Patients will be reassessed daily during the hospital course for medical and nursing stability. To assess outcomes, data from electronic medical records will be used and all patient will be contacted 30 days after hospital admission to assess vital status, rehospitalisation and quality of life measures.

We aim to include between 5000 and 7000 patients over one year of recruitment to derive the three part triage algorithm. The respective main endpoints were defined as (a) initial triage priority (high vs. low priority) adjudicated by the attending ED physician at ED discharge, (b) adverse 30 day outcome (death or intensive care unit admission) within 30 days following ED admission to assess patients risk and thus need for inhospital treatment and (c) care needs after hospital discharge, defined as transfer of patients to a post-acute care institution, for early recognition and planning of post-acute care needs. Other outcomes are time to first physician contact, time to initiation of adequate medical therapy, length of hospital stay, patient's satisfaction with care and overall hospital costs.

Discussion: Using a reliable initial triage system for estimating initial treatment priority, need for inhospital treatment and post-acute care needs is an innovative and persuasive approach for a more targeted management of medical patients in the ED. Our group has proven feasibility with a track record of several completed and ongoing trials. The proposed interdisciplinary project has unprecedented potential to improve initial triage decisions and optimize resource allocation to the sickest patients from admission to discharge. The algorithms derived in this study will be compared in a later randomized controlled trial against a usual care control group in terms of resource use, length of hospital stay, overall costs and patient's outcomes in terms of mortality, rehospitalisation, quality of life and satisfaction with care.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

All consecutive medical patients seeking ED care will be included. There will be no exclusions except for non-adult and non-medical patients. We expect to include 5000 - 8000 patients over one year of recruitment.

Criteria

Inclusion Criteria:

  • All consecutive medical patients seeking ED care

Exclusion Criteria:

  • age below 18 years
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01768494

Contacts
Contact: Philipp Schuetz, PD Dr. med. schuetzph@gmail.com

Locations
Switzerland
University Clinic, Kantonsspital Aarau Recruiting
Aarau, AG, Switzerland, 5000
Contact: philipp schuetz, MD, MPH    41793651006    schuetzph@gmail.com   
Sponsors and Collaborators
University Hospital, Basel, Switzerland
Investigators
Principal Investigator: Philipp Schütz, PD Dr. med. Medical University Clinic, Kantonsspital Aarau, Switzerland
  More Information

No publications provided by University Hospital, Basel, Switzerland

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Philipp Schuetz, PD Dr.med., University Hospital, Basel, Switzerland
ClinicalTrials.gov Identifier: NCT01768494     History of Changes
Other Study ID Numbers: TRIAGE-1
Study First Received: January 9, 2013
Last Updated: April 2, 2013
Health Authority: Switzerland: Ethikkommission

Additional relevant MeSH terms:
Emergencies
Disease Attributes
Pathologic Processes

ClinicalTrials.gov processed this record on November 25, 2014