Longterm Follow-up After Remote Ischemic Preconditioning for Prevention of Contrast-induced Nephropathy (RenProLong)
Remote ischemic preconditioning reduces the incidence of contrast-induced acute kidney injury in patients undergoing elective coronary angiography. This study was designed to acquire long-term data of initially randomized patients in the RenPro Trial.
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Remote Preconditioning for Contrast-Induced Acute Kidney Injury: Long-Term Follow up (RenPro Longterm)|
- MACCE [ Time Frame: 1 Year ] [ Designated as safety issue: Yes ]
Major Adverse Cardiac and Cerebrovascular Events (Combined primary endpoint):
All-cause mortality, cardiovascular mortality, rehospitalization, stroke, myocardial infarction, hemodialysis
- Renal function [ Time Frame: 1 year ] [ Designated as safety issue: Yes ]changes of serum creatinine, eGFR, NGAL and cystatin C compared to baseline in both groups.
|Study Start Date:||July 2012|
|Estimated Study Completion Date:||January 2013|
|Primary Completion Date:||December 2012 (Final data collection date for primary outcome measure)|
Subjects with impaired renal function
Subjects with baseline impaired renal function undergoing cardiac catheterization with contrast-medium exposure
Other: Ischemic preconditioning
Subjects received ischemic preconditioning previous to cardiac catheterization
Data of the RenPro Trial has been already published. In the present study data of longterm follow up are collected.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01760031
|University of Cologne|
|Cologne, NRW, Germany, 50937|
|Principal Investigator:||Fikret Er, MD||University Hospital of Cologne|