Comparison Between Propofol-remifentanil Total Intravenous Anesthesia and Desflurane-remifentanil Balanced Anesthesia With Regard to Post-anesthetic Functional Recovery Measured With QoR-40
This study is not yet open for participant recruitment.
Verified December 2012 by Yonsei University
Sponsor:
Yonsei University
Information provided by (Responsible Party):
Yonsei University
ClinicalTrials.gov Identifier:
NCT01760018
First received: December 31, 2012
Last updated: January 2, 2013
Last verified: December 2012
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Purpose
Total intravenous anesthesia (TIVA) and inhalation anesthesia are both widely and safely used, and there are many clinical trials comparing these on various aspects of anesthesia. However, there have not been studies comparing the quality of recovery from the different methods of general anesthesia. In this study, the investigators compare the functional recovery after general anesthesia in TIVA and inhalation anesthesia with QoR-40 questionnaire.
| Condition | Intervention |
|---|---|
|
Thyroid Operation Under General Anesthesia |
Drug: desflurane group Drug: TIVA group |
| Study Type: | Interventional |
| Study Design: | Allocation: Randomized Endpoint Classification: Efficacy Study Intervention Model: Parallel Assignment Masking: Double Blind (Subject, Investigator) |
Resource links provided by NLM:
Further study details as provided by Yonsei University:
Primary Outcome Measures:
- QoR-40 score [ Time Frame: at 24 hours later after surgery ] [ Designated as safety issue: No ]QoR-40 score is going to be measured at preoperative period, 24 hours, and 48 hours later after surgery.
| Estimated Enrollment: | 80 |
| Study Start Date: | December 2012 |
| Estimated Study Completion Date: | August 2013 |
| Estimated Primary Completion Date: | June 2013 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
| Experimental: Desflurane group |
Drug: desflurane group
anesthesia is maintained with desflurane and remifentanil (Desflurane group)
|
| Active Comparator: TIVA(total intravenous anesthesia) group |
Drug: TIVA group
anesthesia is maintained with fresofol and remifentanil (TIVA group).
|
Eligibility| Ages Eligible for Study: | 20 Years to 65 Years |
| Genders Eligible for Study: | Female |
| Accepts Healthy Volunteers: | No |
Criteria
Inclusion Criteria:
- patients who are undergoing thyroid operation belong to ASA class 1 or 2
Exclusion Criteria:
- patients who are belongs to ASA class 3 or more,
- patients who have underlying complicated cardiovascular or psychological disease.
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01760018
Locations
| Korea, Republic of | |
| Severance Hospital | Not yet recruiting |
| Seoul, Korea, Republic of, 120-752 | |
| Contact: Jeong Rim Lee, MD, Ph.D 82-2-2227-3840 MANYA@yuhs.ac | |
| Principal Investigator: Jeong Rim Lee, MD, Ph.D | |
Sponsors and Collaborators
Yonsei University
More Information
Publications:
| Responsible Party: | Yonsei University |
| ClinicalTrials.gov Identifier: | NCT01760018 History of Changes |
| Other Study ID Numbers: | 4-2012-0748 |
| Study First Received: | December 31, 2012 |
| Last Updated: | January 2, 2013 |
| Health Authority: | South Korea: Institutional Review Board |
Keywords provided by Yonsei University:
|
desflurane, total intravenous anesthesia, QoR-40 |
Additional relevant MeSH terms:
|
Anesthetics Desflurane Remifentanil Central Nervous System Depressants Physiological Effects of Drugs Pharmacologic Actions Central Nervous System Agents Therapeutic Uses |
Anesthetics, Inhalation Anesthetics, General Analgesics, Opioid Analgesics Sensory System Agents Peripheral Nervous System Agents Hypnotics and Sedatives Anesthetics, Intravenous |
ClinicalTrials.gov processed this record on June 13, 2013