Platelet Activation in Chronic Inflammatory Skin Diseases

This study is not yet open for participant recruitment.
Verified December 2012 by Meir Medical Center
Information provided by (Responsible Party):
Meir Medical Center Identifier:
First received: December 28, 2012
Last updated: January 2, 2013
Last verified: December 2012

Platelets are blood cells that are important in coagulation of the blood. These cells have recently been shown to play a role in a number of other biologic processes, for example inflammation. In this study the investigators will determine the extent of platelet activation in people suffering from common chronic skin inflammation-urticaria and allergic dermatitis.

Condition Intervention
Atopic Dermatitis
Procedure: Blood sampling

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by Meir Medical Center:

Primary Outcome Measures:
  • Platelet activation [ Time Frame: 6 months ] [ Designated as safety issue: No ]
    Platelet function will be assessed at enrollment

Secondary Outcome Measures:
  • Mean platelet volume [ Time Frame: 6 months ] [ Designated as safety issue: No ]
    Mean platelet volume will be assessed at enrollment

Estimated Enrollment: 80
Study Start Date: February 2013
Estimated Study Completion Date: October 2013
Estimated Primary Completion Date: August 2013 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Skin disease
Patients with urticaria or atopic dermatitis
Procedure: Blood sampling
Blood sampling
Healthy volunteers
Procedure: Blood sampling
Blood sampling


Ages Eligible for Study:   18 Years to 75 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Hospital clinic


Inclusion Criteria: Urticaria or atopic dermatitis -

Exclusion Criteria:Lack of informed consent


  Contacts and Locations
Please refer to this study by its identifier: NCT01759693

Meir Medical Center Not yet recruiting
Kfar Saba, Israel, 44281
Contact: Martin H Ellis, MD    972-9-7471822   
Sub-Investigator: Martin H Ellis, MD         
Sponsors and Collaborators
Meir Medical Center
  More Information

No publications provided

Responsible Party: Meir Medical Center Identifier: NCT01759693     History of Changes
Other Study ID Numbers: 0113, MMC 0113
Study First Received: December 28, 2012
Last Updated: January 2, 2013
Health Authority: Israel: Ethics Commission

Keywords provided by Meir Medical Center:
Platelet activation

Additional relevant MeSH terms:
Dermatitis, Atopic
Skin Diseases
Skin Diseases, Genetic
Genetic Diseases, Inborn
Skin Diseases, Eczematous
Hypersensitivity, Immediate
Immune System Diseases
Skin Diseases, Vascular processed this record on April 17, 2014