Dexamethasone and Lower Extremity Block Duration
This study is not yet open for participant recruitment.
Verified December 2012 by University of Chicago
Sponsor:
University of Chicago
Information provided by (Responsible Party):
Tariq Malik, University of Chicago
ClinicalTrials.gov Identifier:
NCT01756586
First received: December 20, 2012
Last updated: NA
Last verified: December 2012
History: No changes posted
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Purpose
Dexamethasone has shown to prolong upper extremity blocks. No one ha studied its effect on lower extremity blocks. The study would evaluate that point.
| Condition | Intervention |
|---|---|
|
Analgesia Duration |
Drug: Dexamethasone |
| Study Type: | Interventional |
| Study Design: | Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor) Primary Purpose: Treatment |
Resource links provided by NLM:
Further study details as provided by University of Chicago:
Primary Outcome Measures:
- increase in the duration of block [ Time Frame: one year ] [ Designated as safety issue: No ]
| Estimated Enrollment: | 40 |
| Study Start Date: | February 2013 |
| Estimated Study Completion Date: | December 2013 |
| Estimated Primary Completion Date: | December 2013 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
|
No Intervention: Control
Plain bupivacaine
|
|
|
Experimental: Experimental
Bupivacaine with Dexamethasone
|
Drug: Dexamethasone |
Eligibility| Ages Eligible for Study: | 18 Years to 75 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Criteria
Inclusion Criteria:
- Age 18-75
- foot surgery
- no contraindication to regional anesthesia
Exclusion Criteria:
- opioid dependent
- chronic pain condition
- peripheral neuropathy
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01756586
Contacts
| Contact: Tariq Malik, MD | 773-834-3139 | tmalik@dacc.uchicago.edu |
| Contact: Tariq Malik | 773-834 3646 | tmalik@dacc.uchicago.edu |
Locations
| United States, Illinois | |
| University of Chicago Medical Center | Not yet recruiting |
| Chicago, Illinois, United States, 60637 | |
| Contact: Tariq Malik 773-834-3643 tmalik@dacc.uchicago.edu | |
| Contact: Tariq Malik tmalik@dacc.uchicago.edu | |
| Principal Investigator: Tariq Malik, MD | |
Sponsors and Collaborators
University of Chicago
More Information
No publications provided
| Responsible Party: | Tariq Malik, Assistant Professor, University of Chicago |
| ClinicalTrials.gov Identifier: | NCT01756586 History of Changes |
| Other Study ID Numbers: | IRB12-2198 |
| Study First Received: | December 20, 2012 |
| Last Updated: | December 20, 2012 |
| Health Authority: | United States: Institutional Review Board |
Keywords provided by University of Chicago:
|
popliteal block analgesia duration |
Additional relevant MeSH terms:
|
Dexamethasone acetate Dexamethasone Dexamethasone 21-phosphate BB 1101 Anti-Inflammatory Agents Therapeutic Uses Pharmacologic Actions Antiemetics Autonomic Agents Peripheral Nervous System Agents Physiological Effects of Drugs |
Central Nervous System Agents Gastrointestinal Agents Glucocorticoids Hormones Hormones, Hormone Substitutes, and Hormone Antagonists Antineoplastic Agents, Hormonal Antineoplastic Agents Protease Inhibitors Enzyme Inhibitors Molecular Mechanisms of Pharmacological Action |
ClinicalTrials.gov processed this record on May 22, 2013