Text Size

A Epidemiological Survey of Preoperative Pain Perception and Postoperative Pain in Chinese Population

This study is currently recruiting participants.
Verified December 2012 by Huazhong University of Science and Technology
Sponsor:
Information provided by (Responsible Party):
Zhang Xianwei, Huazhong University of Science and Technology
ClinicalTrials.gov Identifier:
NCT01750047
First received: December 11, 2012
Last updated: December 13, 2012
Last verified: December 2012
History of Changes
  Purpose

Object: Every person's pain perception and possible postoperative pain is different. As the investigators know, they are affected by many factors. However, the investigators don't know whether the smoking factors, alcohol factors, surgery type, education background, etc. will affect individual pain perception and possible postoperative pain in Chinese population. This study was conducted to investigate the power of these possible affect factors. Method: Patients receiving elective surgery under general anesthesia were recruited into this study. The investigators measured their preoperative pressure pain threshold (PPT) and pressure pain tolerance (PTO)and also investigated the patient's personal information of smoking factors, alcohol factors, surgery type, education background, etc. In addition, we retrospectively investigated the visual analog scale (VAS) during patient-controlled analgesia (PCA) treatment 0 h, 12 h ,24 h after operation as well as the PCA press frequency and drug consumption of those patients who received PCA administration.


Condition
Pain
Surgery

Study Type: Observational
Study Design: Time Perspective: Cross-Sectional
Official Title: A Epidemiological Survey of Preoperative Pain Perception and Postoperative Pain in Chinese Population

Resource links provided by NLM:

MedlinePlus related topics: Smoking
U.S. FDA Resources

Further study details as provided by Huazhong University of Science and Technology:

Primary Outcome Measures:
  • Pressure pain threshold [ Time Frame: 1 year ] [ Designated as safety issue: Yes ]
  • Pressure pain tolerance [ Time Frame: 1 year ] [ Designated as safety issue: Yes ]

Secondary Outcome Measures:
  • PCA press frequency after operation [ Time Frame: 1 year ] [ Designated as safety issue: Yes ]
  • Pain scores on visual analog scale after operation [ Time Frame: 1 year ] [ Designated as safety issue: Yes ]
  • Opioid consumption dose after operation [ Time Frame: 1 year ] [ Designated as safety issue: Yes ]

Estimated Enrollment: 3000
Study Start Date: October 2012
Estimated Study Completion Date: December 2013
Estimated Primary Completion Date: October 2013 (Final data collection date for primary outcome measure)
Detailed Description:

Patients with the following diseases were excluded: known history of chronic pain, psychiatric diseases or communication disorders, diabetes mellitus, severe cardiovascular diseases, kidney or liver diseases with poor hepatic function, alcohol or pregnancy or at the lactation period.

  Eligibility

Ages Eligible for Study:   18 Years to 70 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

3000 Chinese patients receiving elective surgery under general anesthesia

Criteria

Inclusion Criteria:

  • Aged 18 to 70
  • The right hand is handedness
  • Agreed to participate the research
  • Not with known chronic disease
  • Not taking analgesics within 3 months

Exclusion Criteria:

  • History of chronic pain diseases
  • Diabetes mellitus
  • Severe cardiovascular diseases
  • Kidney or liver diseases
  • Alcohol or drug abuse
  • Pregnancy or at lactation period
  • Disagree to participate to the research
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01750047

Contacts
Contact: Zhang Xianwei, Doctor (+86)13037154560 znpain@sina.com

Locations
China, Hubei
Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Recruiting
Wuhan, Hubei, China, 430030
Contact: Zhang cai'e, Doctor         zhangcaie1972@126.com    
Principal Investigator: Duan Guangyou, Master            
Sponsors and Collaborators
Zhang Xianwei
Investigators
Principal Investigator: Zhang Xianwei, Doctor Huazhong University of Science and Technology
  More Information

No publications provided

Responsible Party: Zhang Xianwei, Clinical Professor, Huazhong University of Science and Technology
ClinicalTrials.gov Identifier: NCT01750047     History of Changes
Other Study ID Numbers: Pain Epidemiology
Study First Received: December 11, 2012
Last Updated: December 13, 2012
Health Authority: China: Food and Drug Administration

Keywords provided by Huazhong University of Science and Technology:
pain perception
postoperative pain
demography
smoking
alcohol

Additional relevant MeSH terms:
Pain, Postoperative
Postoperative Complications
Pathologic Processes
Pain
Signs and Symptoms

ClinicalTrials.gov processed this record on May 16, 2013