Alterations in Connective Tissue in Patients With or Without Pelvic Organ Prolapse

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Turku University Hospital
ClinicalTrials.gov Identifier:
NCT01749696
First received: December 12, 2012
Last updated: December 13, 2012
Last verified: December 2012
  Purpose

The aim of our study is to investigate the alterations in connective tissue of vaginal wall in patients with and without pelvic organ prolapse (POP).


Condition
Pelvic Organ Prolapse

Study Type: Observational
Official Title: Alterations in Connective Tissue in Patients With or Without Pelvic Organ Prolapse.

Resource links provided by NLM:


Further study details as provided by Turku University Hospital:

Primary Outcome Measures:
  • The elastin content in tissue samples in patients with or without POP. [ Time Frame: september 2012 ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • The collagen content in tissue samples in women with or without POP. [ Time Frame: September 2012 ] [ Designated as safety issue: No ]

Enrollment: 78
Study Start Date: November 2009
Study Completion Date: September 2012
Primary Completion Date: September 2012 (Final data collection date for primary outcome measure)
Groups/Cohorts
Patients with pelvic organ prolapse
Patients, who were operated on because of pelvic organ prolapse.
Patients without pelvic organ prolapse
Patients, who had hysterectomy due to other reasons than pelvic organ prolapse.

  Eligibility

Genders Eligible for Study:   Female
Sampling Method:   Non-Probability Sample
Study Population

39 patients with pelciv organ prolapse and as controls 39 patients without prolapse.

Criteria

Inclusion Criteria:

  • surgery for pelvic organ prolapse
  • hysterectomy due to other reasons than pelvic organ prolapse

Exclusion Criteria:

  • surgery due to malignancy
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01749696

Locations
Finland
Department of Obstetrics and Gynecology, Turku University Central Hospital
Turku, Finland, 20520
Sponsors and Collaborators
Turku University Hospital
  More Information

No publications provided

Responsible Party: Turku University Hospital
ClinicalTrials.gov Identifier: NCT01749696     History of Changes
Other Study ID Numbers: 33/180/2009
Study First Received: December 12, 2012
Last Updated: December 13, 2012
Health Authority: Turku University, Turku, Finland':'

Keywords provided by Turku University Hospital:
Pelvic organ prolapse
Connective tissue
Elastin
Collagen

Additional relevant MeSH terms:
Prolapse
Pelvic Organ Prolapse
Pathological Conditions, Anatomical

ClinicalTrials.gov processed this record on April 17, 2014