Myocardial Perfusion Study to Detect Coronary Microvascular Abnormality in Diabetic Patients With Nonfatal Myocardial Infarction (GEMyCE 1)

This study is currently recruiting participants. (see Contacts and Locations)
Verified December 2012 by State University of New York - Upstate Medical University
Sponsor:
Information provided by (Responsible Party):
State University of New York - Upstate Medical University
ClinicalTrials.gov Identifier:
NCT01749683
First received: December 12, 2012
Last updated: December 13, 2012
Last verified: December 2012
  Purpose

The goal of this study is to use MCE (myocardial contrast/perfusion echocardiography) to study and compare short/long term change of myocardial perfusion abnormality and cardiac outcome in diabetic patients after nonfatal MI (heart attack), who are treated with different glucose control agents.


Condition
Myocardial Infarction

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Myocardial Perfusion Study to Detect Coronary Microvascular Abnormality in Diabetic Patients With Nonfatal Myocardial Infarction

Resource links provided by NLM:


Further study details as provided by State University of New York - Upstate Medical University:

Primary Outcome Measures:
  • Perfusion abnormalities in nondiabetic and diabetic patients [ Time Frame: short term (3 month) and long term (12 month). ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • The effect of different glycemic control strategies on the reduction of coronary injury in diabetic and non-diabetic subjects [ Time Frame: short term (3 month) and long term (12 month) ] [ Designated as safety issue: No ]

Estimated Enrollment: 100
Study Start Date: August 2011
Estimated Primary Completion Date: August 2013 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   18 Years to 71 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Diabetic and nondiabetic patients will be initially recruited and studied after acute nonfatal MI and revascularization with either PCI or CABG

Criteria

Inclusion Criteria:

  • Diabetic and nondiabetic patients will be initially recruited and studied after acute nonfatal MI and revascularization with either PCI or CABG

Exclusion Criteria:

  • Patients are excluded if they are older than 70 year old, require mechanical ventilation, are receiving intravenous pressors or hemodynamic support, or if the motion of segments associated with infarct-related artery can not be accurately determined.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01749683

Contacts
Contact: Kan Liu, MD 315-464-9574 liuk@upstate.edu
Contact: Annie Pennella, MS 315-464-9574 pennella@upstate.edu

Locations
United States, New York
SUNY Upstate Medical University Recruiting
Syracuse, New York, United States, 13210
Contact: Annie Pennella, MS    315-464-9574      
Principal Investigator: Kan Liu, MD         
Sponsors and Collaborators
State University of New York - Upstate Medical University
  More Information

No publications provided

Responsible Party: State University of New York - Upstate Medical University
ClinicalTrials.gov Identifier: NCT01749683     History of Changes
Other Study ID Numbers: GEMyCE1
Study First Received: December 12, 2012
Last Updated: December 13, 2012
Health Authority: United States: Food and Drug Administration

Additional relevant MeSH terms:
Congenital Abnormalities
Infarction
Myocardial Infarction
Ischemia
Pathologic Processes
Necrosis
Myocardial Ischemia
Heart Diseases
Cardiovascular Diseases
Vascular Diseases

ClinicalTrials.gov processed this record on July 29, 2014