UK Genetic Prostate Cancer Study: Epidemiology and Molecular Genetics Studies (UKGPCS)
The UKGPCS was set up to find genetic alterations which occur in patients who have prostate cancer.
A man's risk of developing prostate cancer increases if he has a first-degree relative (father or brother) who was diagnosed with prostate cancer at a young age. This is why we are looking for men who are affected at a young age or who have a family history of prostate cancer, since it is more probable that these prostate cancers are due to an inherited genetic cause rather than an environmental cause.
We also ask all men who come to the Royal Marsden Hospital to be treated for prostate cancer if they would like to take part in the study so that we can also look to see if we find genetic alterations in older men, and those who do not have a family history of prostate cancer.
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||UK Genetic Prostate Cancer Study: Epidemiology and Molecular Genetics Studies|
- To find genes which predispose to PrCa [ Time Frame: 2017 ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples With DNA
Whole blood, Prostate Tissue
|Study Start Date:||January 1993|
|Estimated Study Completion Date:||December 2017|
|Estimated Primary Completion Date:||December 2012 (Final data collection date for primary outcome measure)|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01737242
|Contact: Rosalind A Eeles, FRCP FRCRfirstname.lastname@example.org|
|Institute of Cancer Research and Royal Marsden Hospital||Recruiting|
|Sutton, Surrey, United Kingdom, SM2 5PT|
|Contact: Rosalind A Eeles, FRCP FRFR 02086613642 email@example.com|
|Principal Investigator: Rosalind A Eeles, FRCP FRCR|
|Principal Investigator:||Rosalind A Eeles, FRCP FRCR||Institute of Cancer Research and Royal Marsden Hospital|