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The Effect of Video Game Exercise on Dynamic Balance and Gait in Individuals With Huntington's Disease

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Anne Kloos, The Ohio State University
ClinicalTrials.gov Identifier:
NCT01735981
First received: November 7, 2012
Last updated: November 21, 2012
Last verified: November 2012
History of Changes
  Purpose

To examine the benefits of using a video-game, Dance, Dance, Revolution, as an exercise modality to improve gait and balance in individuals with Huntington's disease.


Condition Intervention
Huntington's Disease
 Other: Video game exercise using Dance Dance Revolution
Other: hand-held video game

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Crossover Assignment
Masking: Single Blind (Investigator)
Primary Purpose: Treatment
Official Title: The Effect of Video Game Biofeedback Modulated Exercise (ViBE)on Dynamic Balance and Gait in Individuals With Huntington's Disease

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Ohio State University:

Primary Outcome Measures:
  • gait parameters [ Time Frame: post intervention and post hand-held game, each of these phases lasts 6 weeks ] [ Designated as safety issue: No ]
    utilized GAITRite to obtain spatiotemporal measures of gait with velocity being the primary measure.


Secondary Outcome Measures:
  • Tinetti Mobility Test [ Time Frame: post intervention and post hand-held game, each lasts 6 weeks ] [ Designated as safety issue: No ]
    observation of gait and balance with quantifiable assessment on a scale of 0-2

  • Four Square Step Test [ Time Frame: post intervention and post hand-held game, each lasts 6 weeks ] [ Designated as safety issue: No ]
    examines ability to step in multiple directions. timed.

  • Unified Huntington's Disease Scale, motor scale [ Time Frame: post intervention and post hand-held game, each lasts 6 weeks ] [ Designated as safety issue: No ]
    measure of disease severity

  • Unified Huntington's Disease Rating Scale cognitive measure [ Time Frame: post intervention and post hand-held game, each lasts 6 weeks ] [ Designated as safety issue: No ]
    cognitive battery that is part of the standard Unified Huntington's Disease Rating Scale clinical assessment.

  • Activities-Specific Balance Confidence scale [ Time Frame: post intervention and post hand-held game, each lasts 6 weeks ] [ Designated as safety issue: No ]
    measures confidence and fear of falling

  • World Health Organization Quality of Life [ Time Frame: post intervention and post hand-held game, each lasts 6 weeks ] [ Designated as safety issue: No ]
    a measure of quality of life


Enrollment: 24
Study Start Date: June 2008
Study Completion Date: June 2012
Primary Completion Date: November 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: video game exercise
Video game exercise using Dance Dance Revolution
 Other: Video game exercise using Dance Dance Revolution
use of the video-game, Dance, Dance Revolution as an exercise to improve gait and balance
Other Names:
  • exercise
  • video-game based exercise
control
hand-held video game control
 Other: hand-held video game
hand-held video games
Other Name: hand-held video game

Detailed Description:

The primary purpose of this study was to determine the effectiveness of a therapist-guided Video-game Biofeedback Modulated Exercise (ViBE) program administered via Dance Dance Revolution to improve dynamic balance, gait and mobility in individuals with Huntington's Disease. Secondary aims were to explore whether the ViBE intervention would improve quality of life, fall risk, and neuropsychological functions. The investigators hypothesized that the video-game program would lead to greater improvements in walking, dynamic balance, quality of life, fall risk, and neuropsychological function than a control handheld video game program. Since motivation is essential to the long-term maintenance of an exercise program the investigators were also interested in finding out how successful people with Huntington's Disease were at playing Dance Dance Revolution, what their perceptions were of playing the game, and whether they thought that it was beneficial

  Eligibility

Ages Eligible for Study:   18 Years to 79 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • adults 18 - 79 with a diagnosis of Huntington's disease

Exclusion Criteria:

  • cannot walk 10 feet without assistance, any other neurologic condition
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01735981

Locations
United States, Ohio
The Ohio State University Atwell Hall
Columbus, Ohio, United States, 43210
Sponsors and Collaborators
Anne Kloos
Investigators
Principal Investigator: Deb Kegelmeyer, DPT, MS Ohio State University
Principal Investigator: Anne Kloos, PT, PhD Ohio State University
  More Information

No publications provided

Responsible Party: Anne Kloos, Associate Professor Clinical Health and Rehabilitation Sciences, The Ohio State University
ClinicalTrials.gov Identifier: NCT01735981     History of Changes
Other Study ID Numbers: 2008H0109
Study First Received: November 7, 2012
Last Updated: November 21, 2012
Health Authority: United States: Institutional Review Board

Keywords provided by Ohio State University:
Huntington's Disease
gait
exercise
balance
video game

Additional relevant MeSH terms:
Huntington Disease
Basal Ganglia Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Dementia
Chorea
Dyskinesias
 Movement Disorders
Heredodegenerative Disorders, Nervous System
Neurodegenerative Diseases
Genetic Diseases, Inborn
Cognition Disorders
Delirium, Dementia, Amnestic, Cognitive Disorders
Mental Disorders

ClinicalTrials.gov processed this record on May 16, 2013