Assessing the Effects of Air-cooling on Capillary Malformations
The purpose of this observational study is to ascertain the effects of cutaneous air cooling on vessel diameter within Capillary Malformations (CM).
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||An Observational Study as to the Effects of Cutaneous Air-cooling on Blood Vessel Diameter in Capillary Malformations|
- To study the effects of cutaneous air cooling on blood vessel diameter in capillary malformation [ Time Frame: 10 minutes ] [ Designated as safety issue: No ]In a temperature controlled room, the participant's capillary diameter/depth and skin/core temperatures will be taken from their CM prior to cooling the skin. The patients' CM will be cooled for a duration of 1 minute. The above measurements will be repeated immediately after 1 minute of cooling.
|Study Start Date:||February 2013|
|Estimated Study Completion Date:||November 2013|
|Estimated Primary Completion Date:||November 2013 (Final data collection date for primary outcome measure)|
Capillary malformation (CM) is the most common vascular malformation occurring in approximately 0.3% of all newborn. The standard treatment for facial or aesthetically sensitive CM's is flashlamp Pulsed Dye Laser. Skin cooling prior to laser treatment of CMs is standard practice within our department. The effects of skin cooling on the vasculature within CMs are poorly understood. Previous studies by our department have shown that raising ambient temperature increases CM vessel size. It has been postulated that by increasing CM vessel size, it may also increase the effectiveness of treatment. We hypothesize that cooling the skin during laser treatment may cause vasconstriction of the superficial vessels within the CM. This may have an impact on treatment success.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01735734
|Contact: Irving Ling, MBBSfirstname.lastname@example.org|
|Canniesburn Plastic Surgery Unit, Glasgow Royal Infirmary||Not yet recruiting|
|Glasgow, United Kingdom, G4 0SF|
|Principal Investigator: Irving Ling, MBBS|
|Principal Investigator:||Irving Ling, MBBS||NHS Greater Glasgow and Clyde|
|Study Chair:||Adam Gilmour, MBChB, MRCS (Ed)||NHS Greater Glasgow and Clyde|
|Study Director:||Iain Mackay, MBChb, MRCS, FRCS (plast)||NHS Greater Glasgow and Clyde|