tDCS to Enhance Cognitive Training in Schizophrenia
The primary aim for the study is to determine whether transcranial direct current stimulation (tDCS) enhances training gains on cognitive training (CT) tasks. Secondary aims are to determine whether tDCS combined with CT causes larger transferable improvements on non-trained tasks (i.e., generalisation effects) and whether these generalisation effects are maintained over time (i.e., maintenance effects).
Specific hypotheses are:
- CT combined with active tDCS will produce greater training gains on CT tasks compared to a similar control group receiving CT with sham tDCS.
- CT combined with active tDCS will produce greater generalisation effects on non-trained cognitive tasks compared to CT with sham tDCS.
- The cognitive improvements gained by patients from both interventions will be maintained over 1 month follow-up.
Device: transcranial direct current stimulation
|Study Design:||Allocation: Randomized
Masking: Double Blind (Subject, Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:||Does Transcranial Direct Current Stimulation (tDCS) Enhance Outcomes From Computerised Cognitive Remediation in Patients With Schizophrenia?|
- Progression score on cognitive training task.
|Study Start Date:||November 2012|
|Experimental: active tDCS and cognitive training||Device: transcranial direct current stimulation|
|Active Comparator: sham tDCD and cognitive training||Device: transcranial direct current stimulation|
|Contact: Aparna Menon, MD||61 2 9540 8232||AparnaMenon.TarurPadinjareveet@sesiahs.health.nsw.gov.au|
|Australia, New South Wales|
|Mental Health Rehabilitation Unit (MHRU) at the Sutherland hospital||Recruiting|
|Sydney, New South Wales, Australia, 2229|
|Contact: Aparna Menon, MD 61 2 9540 8232 AparnaMenon.TarurPadinjareveet@sesiahs.health.nsw.gov.au|
|Principal Investigator: Aparna Menon, MD|