The Learning and Memory of the Experience of Pain

This study is currently recruiting participants.
Verified March 2014 by Massachusetts General Hospital
Information provided by (Responsible Party):
Jian Kong, Massachusetts General Hospital Identifier:
First received: November 16, 2012
Last updated: March 25, 2014
Last verified: March 2014

This study investigates the learning and memory of pain.

Condition Intervention
Behavioral: Learning and Memory of Pain

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Single Blind (Subject)

Resource links provided by NLM:

Further study details as provided by Massachusetts General Hospital:

Estimated Enrollment: 60
Study Start Date: January 2013
Estimated Study Completion Date: December 2016
Estimated Primary Completion Date: January 2015 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  1. Male and female healthy volunteers.
  2. 18-65 years of age.
  3. Right-handed.
  4. Fluency in English. Ability to read and understand English; English can be a second language provided that the participant feels that he/she is able to understand all the questions used in the assessment measures.

Exclusion Criteria:

  1. Any previous experience with conditioned analgesia/hyperalgesia paradigms.
  2. Presence of any illness or medication use that is judged to interfere with the trial. For example: psychiatric disorder according to the DSM-IV manual, medication that can influence cognition or emotional processing, i.e. sleep medication, antidepressants, anti-convulsants or opioids.
  3. Unwillingness to receive brief pain stimulation administered by a heat probe on the hand.
  4. Instability of responses to experimental heat pain
  5. Any contraindications to fMRI scanning for subjects in Experiment 2 (including metal implants, claustrophobia, history of head trauma, and pregnancy).
  6. Peripheral neuropathy.
  Contacts and Locations
Please refer to this study by its identifier: NCT01731314

Contact: Jacky Yu 617-643-7946

United States, Massachusetts
MGH East Campus, 149 13th St. Recruiting
Charlestown, Massachusetts, United States, 02129
Contact: Jacky Yu         
Sponsors and Collaborators
Massachusetts General Hospital
  More Information

No publications provided

Responsible Party: Jian Kong, MS, MD, Massachusetts General Hospital Identifier: NCT01731314     History of Changes
Other Study ID Numbers: 2012P002386
Study First Received: November 16, 2012
Last Updated: March 25, 2014
Health Authority: United States: Institutional Review Board processed this record on April 16, 2014