Ribose and Sport Performance

This study is ongoing, but not recruiting participants.
Sponsor:
Collaborator:
Atrium Innovations
Information provided by (Responsible Party):
Laval University
ClinicalTrials.gov Identifier:
NCT01727479
First received: November 2, 2012
Last updated: November 24, 2012
Last verified: November 2012
  Purpose

Investigate the acute effect of ribose supplementation on performance and recovery in athletes.


Condition Intervention
Sports
Other: Ribose
Other: Placebo

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Crossover Assignment
Masking: Double Blind (Subject, Investigator, Outcomes Assessor)
Primary Purpose: Prevention
Official Title: The Effect of Ribose on Performance and Recovery in Athletes

Further study details as provided by Laval University:

Primary Outcome Measures:
  • Change in time to complete the third of 3 consecutive 3km time trials on bike [ Time Frame: baseline and 1 week ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Performance on the 3 consecutive 3km time trials on bike [ Time Frame: baseline and 1 week ] [ Designated as safety issue: No ]
    Performance measures: peak power (watts/kg), mean power (watts/kg), time to peak power (sec), total work (kJ) and maximum cadence (RPMmax)


Other Outcome Measures:
  • Fatigue perception after each of the 3 consecutive 3km time trials on bike [ Time Frame: baseline and 1 week ] [ Designated as safety issue: No ]
    Post-exercise fatigue perception on visual analog scale (VAS)

  • Peak Vo2 consumption during each of the 3km time trials on bike [ Time Frame: baseline and 1 week ] [ Designated as safety issue: No ]

Estimated Enrollment: 18
Study Start Date: August 2012
Primary Completion Date: November 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Ribose
After each of the 3km time trial (3 in total), consumption of ribose incorporated in a sports drink.
Other: Ribose
After each of the 3km time trial (3 in total), participants will be asked to drink the experimental product (or placebo) incorporated in a sports drink.
Placebo Comparator: Placebo
After each of the 3km time trial (3 in total), consumption of placebo incorporated in a sports drink.
Other: Placebo

  Eligibility

Ages Eligible for Study:   18 Years to 50 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Men and women
  • Training volume > 7hrs/week
  • VO2 max > 40 and 45 mg/kg/min (for women and men respectively)
  • Otherwise healthy individuals

Exclusion Criteria:

  • Pregnant or breastfeeding women
  • Individuals with endocrine disorders, hypercholesterolemia, cardiovascular diseases, gut diseases, cancer, anemia, hypoglycemia
  • Medication for lipids, diabetes, hypertension, inflammation, autoimmune diseases, mood disorders
  • Excessive alcohol consumption (more than two drinks by day for men, one for women), smoking, drug use, supplements or natural products consumption during the study
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01727479

Locations
Canada, Quebec
Université Laval
Québec, Quebec, Canada, G1V0A6
Sponsors and Collaborators
Laval University
Atrium Innovations
Investigators
Principal Investigator: Benoît Lamarche, PhD Institute on nutraceuticals and functional foods
  More Information

No publications provided

Responsible Party: Laval University
ClinicalTrials.gov Identifier: NCT01727479     History of Changes
Other Study ID Numbers: 2012-048, INAF-2012-048
Study First Received: November 2, 2012
Last Updated: November 24, 2012
Health Authority: Canada: Health Canada

Keywords provided by Laval University:
Peak VO2 consumption
3km time trial
fatigue perception
lactate
time to complete

ClinicalTrials.gov processed this record on September 16, 2014