Sugars-containing Beverage and Food Intake in Children

This study has been completed.
Sponsor:
Collaborator:
Mount Saint Vincent University
Information provided by (Responsible Party):
Nick Bellissimo, Ryerson University
ClinicalTrials.gov Identifier:
NCT01717716
First received: October 23, 2012
Last updated: October 26, 2012
Last verified: October 2012
  Purpose

The purpose is to determine the effect of sugars in solution on food intake and subjective appetite in 9- to 14-year-old normal weight boys. The investigators hypothesize that food intake after all sugars-containing solutions will be decreased in comparison to the control solution, with similar reductions in FI between high-fructose corn syrup -55 (HFCS-55) and sucrose. Food intake will be measured 60 minutes after consumption of 50g of HFCS-55, sucrose or glucose, or a control treatment. Subjective appetite will be measured at 15, 30, 45, 60 and 90 minutes.


Condition Intervention
Childhood Obesity
Dietary Supplement: water with Sucralose
Dietary Supplement: water with HFCS
Dietary Supplement: water with glucose
Dietary Supplement: water with sucrose

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single Blind (Subject)
Primary Purpose: Prevention
Official Title: Role of Sugars in Solution on Subjective Appetite and Short-term Food Intake in Normal Weight 9-14 Year Old Boys

Resource links provided by NLM:


Further study details as provided by Ryerson University:

Primary Outcome Measures:
  • Food intake (kcal) [ Time Frame: measured at 60 minutes after the treatment ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Subjective appetite (mm) [ Time Frame: 0-90 minutes ] [ Designated as safety issue: No ]
    Subjective appetite (in mm) by visual analogue scale will be determined at 0, 15, 30, 45, 60 and 90 minutes.


Enrollment: 15
Study Start Date: June 2011
Study Completion Date: September 2011
Primary Completion Date: September 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Calorie-free control
Calorie-free control
Dietary Supplement: water with Sucralose
Experimental: HFCS-55 drink
HFCS-55 drink
Dietary Supplement: water with HFCS
Experimental: Glucose drink
Glucose drink
Dietary Supplement: water with glucose
Experimental: Sucrose drink
Sucrose drink
Dietary Supplement: water with sucrose

  Eligibility

Ages Eligible for Study:   9 Years to 14 Years
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Healthy, boy, born at full term and normal birth weight

Exclusion Criteria:

  • Girl, on restricted diet, taking medication that affect appetite or food intake, have significant learning, behavioral, or emotional difficulties
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01717716

Locations
Canada, Nova Scotia
Department of Applied Human Nutrition
Bedford, Nova Scotia, Canada
Sponsors and Collaborators
Ryerson University
Mount Saint Vincent University
Investigators
Principal Investigator: Nick Bellissimo, PhD Ryerson University
  More Information

No publications provided

Responsible Party: Nick Bellissimo, Assistant Professor, Ryerson University
ClinicalTrials.gov Identifier: NCT01717716     History of Changes
Other Study ID Numbers: REB 2010-017-001
Study First Received: October 23, 2012
Last Updated: October 26, 2012
Health Authority: Canada: Ethics Review Committee

Keywords provided by Ryerson University:
boys
obesity
glucose
sucrose
high-fructose corn syrup-55

Additional relevant MeSH terms:
Obesity
Pediatric Obesity
Overnutrition
Nutrition Disorders
Overweight
Body Weight
Signs and Symptoms

ClinicalTrials.gov processed this record on October 02, 2014