Symptom Clusters in Children With Leukemia
The purpose of this study is to examine the phenotypic and genotypic characteristics and their associations with symptom clusters experienced during treatment for childhood leukemia.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Phenotypic and Genotypic Associations With Symptom Clusters During Childhood Leukemia Treatment|
A baseline CSF sample will be obtained prior to intrathecal chemotherapy. CSF biomarkers will be obtained at the initiation of post-induction, 4 and 6 months into post-induction therapy, and at the start of maintenance therapy.A saliva sample will be obtained for genotypic analysis at one of the four data collection times.
|Study Start Date:||November 2012|
|Estimated Study Completion Date:||July 2017|
|Estimated Primary Completion Date:||July 2017 (Final data collection date for primary outcome measure)|
A repeated measures research design will evaluate phenotypic and genotypic treatment-related symptom associations experienced by children and adolescents 3-17 years of age with a diagnosis of leukemia.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01708421
|United States, North Carolina|
|Duke University Medical Center|
|Durham, North Carolina, United States, 27710|
|Principal Investigator:||Marilyn Hockenberyy, PhD||Duke University School of Nursing|