Influence of Inspiratory Flow Pattern on Exchange of Carbon Dioxide in Humans Without Primary Lung Disease
This study is currently recruiting participants.
Verified March 2013 by Region Skane
Sponsor:
Region Skane
Information provided by (Responsible Party):
Region Skane
ClinicalTrials.gov Identifier:
NCT01686984
First received: September 13, 2012
Last updated: March 11, 2013
Last verified: March 2013
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Purpose
The purpose of this study is to investigate how inspiratory flow pattern influences CO2 elimination in people without primary lung disease.
The hypothesis is that a long mean distribution time, caused by a long postinspiratory pause and high end-inspiratory flow, will promote CO2 exchange in the alveoli.
| Condition | Intervention |
|---|---|
|
Pulmonary Gas Exchange Carbon Dioxide |
Other: Altered breath |
| Study Type: | Interventional |
| Study Design: | Endpoint Classification: Efficacy Study Intervention Model: Single Group Assignment Masking: Open Label Primary Purpose: Basic Science |
| Official Title: | Influence of Inspiratory Flow Pattern on Exchange of Carbon Dioxide in Humans Without Primary Lung Disease |
Resource links provided by NLM:
Further study details as provided by Region Skane:
Primary Outcome Measures:
- Carbon dioxide elimination in a ventilator assisted breath. [ Time Frame: 30 minutes ] [ Designated as safety issue: No ]
Secondary Outcome Measures:
- Blood CO2 concentration. [ Time Frame: 30 minutes ] [ Designated as safety issue: No ]
| Estimated Enrollment: | 10 |
| Study Start Date: | September 2012 |
| Estimated Study Completion Date: | September 2013 |
| Estimated Primary Completion Date: | September 2013 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
|
Experimental: Altered breath
The group where the investigators alter the inspiratory and expiratory aspects of a ventilated breath.
|
Other: Altered breath |
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Criteria
Inclusion Criteria:
- No known primary lung disease
Exclusion Criteria:
- Primary lung disease
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01686984
Contacts
| Contact: Gunnar Malmkvist, Med.Dr | +4646-171035 | gunnar.malmkvist@skane.se |
Locations
| Sweden | |
| Division of Brain, Heart and Lungs, Neurosurgical Clinic, Skane University Hospital, Lund | Recruiting |
| Lund, Skane, Sweden, 22185 | |
| Contact: Samuel Allvin, Med. Student +46706607477 samuelallvin@gmail.com | |
Sponsors and Collaborators
Region Skane
Investigators
| Principal Investigator: | Mikael Bodelsson, Professor | Division of Anesthesia, Skane University Hospital, Lund, Sweden |
More Information
No publications provided
| Responsible Party: | Region Skane |
| ClinicalTrials.gov Identifier: | NCT01686984 History of Changes |
| Other Study ID Numbers: | 2012/381 |
| Study First Received: | September 13, 2012 |
| Last Updated: | March 11, 2013 |
| Health Authority: | Sweden: Swedish Medical Product Agency |
Additional relevant MeSH terms:
|
Respiratory Aspiration Lung Diseases Respiration Disorders |
Respiratory Tract Diseases Signs and Symptoms, Respiratory Signs and Symptoms |
ClinicalTrials.gov processed this record on May 23, 2013