Comparison of Cardiac Rehabilitation Benefits Between Coronary and Non-coronary Patients Through a 24 Months Follow-up After Myocardial Infarction: the "INCARD" Study

• Change in VO2max every 6 months over the 24 months [ Time Frame: every 6 months over the 24 months of outpatient follow-up ] [ Designated as safety issue: No ]
  VO2max (L)
  
  
• Change in Left ventricular ejection fraction every 6 months over the 24 months of outpatient follow-up [ Time Frame: every 6 months over the 24 months of outpatient follow-up ] [ Designated as safety issue: No ]
  Left ventricular ejection fraction (ultrasound method and/or isotopic) in %
  
  
• Change on 6-min walk test every 6 months over the 24 months [ Time Frame: every 6 months over the 24 months of outpatient follow-up ] [ Designated as safety issue: No ]
  6-min walk test (m)
  
  
• Change on Minnesota index of quality of life every 6 months over the 24 months [ Time Frame: every 6 months over the 24 months of outpatient follow-up ] [ Designated as safety issue: No ]
  Minnesota index of quality of life.
  
  
• Change on heart rate every 6 months over the 24 months [ Time Frame: every 6 months over the 24 months of outpatient follow-up ] [ Designated as safety issue: No ]
  Heart rate (bpm)
  
  
• Change on systolic blood pressure every 6 months over the 24 months [ Time Frame: every 6 months over the 24 months of outpatient follow-up ] [ Designated as safety issue: No ]
  systolic blood pressure (mmHg)
  
  
• Change on diastolic blood pressure every 6 months over the 24 months [ Time Frame: every 6 months over the 24 months of outpatient follow-up ] [ Designated as safety issue: No ]
  diastolic blood pressure (mmHg)
  
  
• Change on body mass index every 6 months over the 24 months [ Time Frame: every 6 months over the 24 months of outpatient follow-up ] [ Designated as safety issue: No ]
  Measurement of weight and height, calculation of body mass index (kg/m2)
  
  
• Change on creatine clearance every 6 months over the 24 months [ Time Frame: every 6 months over the 24 months of outpatient follow-up ] [ Designated as safety issue: No ]
  creatine clearance (ml/min)
  
  

We will undertake a prospective follow-up study of 150 rehabilitated patients with heart failure (75 C; 75 NC). The main objective will be to compare the benefits of rehabilitation between coronary and non-coronary patients based on functional improvement i.e. improvements of VO2max, LVEF (ultrasound method and/or isotopic), 6-min walk test, Minnesota index of quality of life. In addition, clinical outcomes (HR, SBP, DBP, BMI) and paraclinical data (creatinine clearance) will be measured as patients' standard clinical follow-up .

Clinical data of the patients admitted to the cardiac rehabilitation, including heart failure patients (LVEF <40), will be recorded after collection of their signed informed consent agreement. Patients will be addressed from heart failure intensive care units for coronary (USIC) or acute cardiac services to the rehabilitation department. Patients will be admitted in the rehabilitation department when there are clinically stable (at least three weeks after the acute episode). Etiology of the heart failure will be assessed and patients stratified as C or NC patients.

Expected Results We will estimate the mean duration of inpatient rehabilitation (H period). Then, we will follow patients' cardiac evaluation parameters recorded from an outpatient follow-up, first 3 months after inclusion and then every 6 months over the 24 months of outpatient follow-up.

These data will allow for comparison of the benefits of rehabilitation between coronary (C) and non-coronary (NC) patients for each evaluation time point and will give information on the clinical improvement of each group of patients.